Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements.
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Human thrombomodulin gene is intron depleted: nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory controlFusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocationPhosphorylation of E47 as a potential determinant of B-cell-specific activityA conserved CATTCCT motif is required for skeletal muscle-specific activity of the cardiac troponin T gene promoterAKT induces transcriptional activity of PU.1 through phosphorylation-mediated modifications within its transactivation domainOct-2 regulates CD36 gene expression via a consensus octamer, which excludes the co-activator OBF-1.Evolution of the casein multigene family: conserved sequences in the 5' flanking and exon regionsAn inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 geneNonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdissSR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeatComplex regulation of the muscle-specific contractile protein (troponin I) geneA weakened transcriptional enhancer yields variegated gene expressionEnforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development.Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences.Oligonucleotide that binds nuclear factor NF-kappa B acts as a lymphoid-specific and inducible enhancer element.T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.Poly(A) site choice rather than splice site choice governs the regulated production of IgM heavy-chain RNAs.Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoterThe spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements.Identification of murine nuclear proteins that bind to the conserved octamer sequence of the immunoglobulin promoter region.A promoter element that exerts positive and negative control of the interleukin 2-responsive J-chain gene.Characterization and expression of the murine CD3-epsilon gene.Evidence for a trans-acting factor that regulates the transcription of class II major histocompatibility complex genes: genetic and functional analysis.Down-regulation of c-myb gene expression is a prerequisite for erythropoietin-induced erythroid differentiation.Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-cateninSynergistic action of GA-binding protein and glucocorticoid receptor in transcription from the mouse mammary tumor virus promoter.A single amino acid substitution in the variable region of the light chain specifically blocks immunoglobulin secretionHormonal and developmental specificities of transcription lie within a 1.5 kb region 5' to the ecdysone inducible Drosophila P1 gene.The first exon of the c-myc proto-oncogene contains a novel positive control element.Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrateThe conserved decanucleotide from the immunoglobulin heavy chain promoter induces a very high transcriptional activity in B-cells when introduced into an heterologous promoter.Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic miceCell-type preference of immunoglobulin kappa and lambda gene promotersSeparable cis-acting control elements for expression of the white gene of DrosophilaNuclear factors that bind two regions important to transcriptional activity of the simian immunodeficiency virus long terminal repeatIdentification of NF-jun, a novel inducible transcription factor that regulates c-jun gene transcription.An RNA polymerase pause site is associated with the immunoglobulin mus poly(A) siteTissue-specific genetic variation in the level of mouse alcohol dehydrogenase is controlled transcriptionally in kidney and posttranscriptionally in liverRecognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors.Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein.
P2860
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P2860
Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh-hant
name
Cell-type specificity of immun ...... t three DNA sequence elements.
@en
Cell-type specificity of immun ...... t three DNA sequence elements.
@nl
type
label
Cell-type specificity of immun ...... t three DNA sequence elements.
@en
Cell-type specificity of immun ...... t three DNA sequence elements.
@nl
prefLabel
Cell-type specificity of immun ...... t three DNA sequence elements.
@en
Cell-type specificity of immun ...... t three DNA sequence elements.
@nl
P1433
P1476
Cell-type specificity of immun ...... t three DNA sequence elements.
@en
P2093
Baltimore D
Grosschedl R
P304
P356
10.1016/S0092-8674(85)80069-6
P407
P577
1985-07-01T00:00:00Z