Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
about
Molecular robots guided by prescriptive landscapes.Collagen fibril architecture, domain organization, and triple-helical conformation govern its proteolysisA cancer cell metalloprotease triad regulates the basement membrane transmigration programArtificial Molecular MachinesBiophysical studies of matrix metalloproteinase/triple-helix complexesMatrix metalloproteinase interactions with collagen and elastinInternal strain drives spontaneous periodic buckling in collagen and regulates remodeling.High-speed atomic force microscopy reveals strongly polarized movement of clostridial collagenase along collagen fibrils.Structure of collagenase G reveals a chew-and-digest mechanism of bacterial collagenolysisStructural basis for matrix metalloproteinase 1-catalyzed collagenolysis.Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decadeStrategies of eradicating glioma cells: a multi-scale mathematical model with MiR-451-AMPK-mTOR controlThe use of residual dipolar coupling in studying proteins by NMR.Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence.Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins.The roles of substrate thermal stability and P2 and P1' subsite identity on matrix metalloproteinase triple-helical peptidase activity and collagen specificity.Direct visualization of protease action on collagen triple helical structure.Compartmentalization by directional gene expression.Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA NanostructureMolecular mechanism of type I collagen homotrimer resistance to mammalian collagenases.Diffusion of MMPs on the surface of collagen fibrils: the mobile cell surface-collagen substratum interface.miR451 and AMPK mutual antagonism in glioma cell migration and proliferation: a mathematical modelFluorescence correlation spectroscopy: past, present, future.An autonomous and controllable light-driven DNA walking device.Localizing matrix metalloproteinase activities in the pericellular environment.PMAP: databases for analyzing proteolytic events and pathways.Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer.Activation of EDTA-resistant gelatinases in malignant human tumors.The recognition of collagen and triple-helical toolkit peptides by MMP-13: sequence specificity for binding and cleavageThe anomalous diffusion of a tumor invading with different surrounding tissuesWhole cell mechanics of contractile fibroblasts: relations between effective cellular and extracellular matrix moduliForespore engulfment mediated by a ratchet-like mechanism.Single-molecule tracking of collagenase on native type I collagen fibrils reveals degradation mechanism.Matrix metalloprotease-1a promotes tumorigenesis and metastasis.Weak alignment of biomacromolecules in collagen gels: an alternative way to yield residual dipolar couplings for NMR measurementsRegulation of cell proliferation and migration in glioblastoma: new therapeutic approachInterstitial collagen catabolism.The Need for Integrative Computational Oncology: An Illustrated Example through MMP-Mediated Tissue Degradation.Examination of matrix metalloproteinase-1 in solution: a preference for the pre-collagenolysis state.Chemical biology for understanding matrix metalloproteinase function.
P2860
Q24605627-76801A77-F391-4F37-BC62-9EA3A4292139Q24652849-A522BDB9-8440-45FC-B4DA-9DC655276DADQ24669726-D5CB897B-AFFC-40FE-A993-1888CE450C2CQ26783064-1B4C3B89-2A57-4A0E-8CF1-4876A224BFD6Q26866074-03A24A14-44C1-4E8D-9E89-8914B3FF5A57Q26996437-8195173F-1064-4644-B8F1-AA815FF2C9BDQ27316850-DC4F9282-0794-4482-B80A-6472292D9C3DQ27334060-E49BB763-1CA9-4F50-9739-5940043E4D12Q27674472-52E0C418-C5C1-48CE-ADAD-568B0977B8D1Q27676701-6D2A67E4-8609-4DAB-97FA-D6AF41A7B286Q28288148-4F1C659C-8ADA-4AC2-AF47-7465AD1409A8Q28543125-062490BC-2D85-4073-8BB1-18BB08635021Q30407518-ABD1FB67-3C42-40EA-9F22-3AF889DD86FDQ30483791-E70A9A98-A621-4A37-AF6E-B175CED5B757Q30576104-945F8001-4CC3-427D-9A1E-18340B6EDF4DQ33261566-9EA2E2F1-1F95-487D-9AF7-C9B4FCA46CA9Q33618881-8FC21AB9-FAAD-4E54-B82C-177481BA2864Q33734111-45684A21-CF94-4E7D-AC6F-9A85C2EF96C6Q33899001-A6D369D6-6EA2-4C10-AFCB-20740AADEC0AQ33991179-871A2BA5-5F49-4F54-98EE-917440132461Q34017819-E8E3D5E0-217E-433D-8BF9-B1DBEF4964DFQ34113536-C9EEA330-D734-44AD-9A4A-6056935372B8Q34114385-7A11879A-13D4-4E50-88BD-85609A581C21Q34251281-78B01CEB-C70B-4179-A406-6F354D7F89F3Q34418625-F0394831-BBEA-42D4-86A2-EB4D8B04CA84Q34848387-B4C5E97F-B43E-41F8-A4EC-3EB31CAF6B44Q34884623-218DA5D3-D050-4BD1-8BC2-DD0BEFE43E99Q35113892-10579F6C-E88B-4A78-AC97-8F28A9EAD865Q35204098-3A547774-91D4-4C21-BDE2-01CF407A1A22Q35326386-677F964D-B76F-427F-B0E6-53B442ABC07AQ35687972-8199210A-5012-423E-A572-B46F9EE6B0A5Q35699301-072E0478-B4CF-4821-BB74-04EFD6D902B2Q36055116-28B32CEE-DE80-4ED9-9B2E-CD34ECE040B1Q36097959-B55A1A92-C86A-4317-B220-E60CE2F26224Q36567041-52FB98DA-CFAA-4973-865B-CAF480ABCF2EQ36693243-B9728411-F5DC-43F6-99A8-FDAB92989980Q36724874-E0DB6DE2-60F7-4066-A2B3-A1D06DD37BBCQ37046915-2839CD51-6A34-41AE-8F2D-FDAE0337BBB4Q37234116-FCC90F59-F3C4-4A92-BE7D-6DF1B4CD83C8Q37632925-B97FE215-7E4F-4AB8-913F-00AFE882F20E
P2860
Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
@en
Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
@nl
type
label
Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
@en
Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
@nl
prefLabel
Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
@en
Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
@nl
P2093
P356
P1433
P1476
Interstitial collagenase is a Brownian ratchet driven by proteolysis of collagen.
@en
P2093
Barry L Marmer
Elliot L Elson
Gregory Goldberg
Ivan E Collier
Saveez Saffarian
P304
P356
10.1126/SCIENCE.1099179
P407
P577
2004-10-01T00:00:00Z