Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation.
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Structural Basis of the CD8 /MHC Class I Interaction: Focused Recognition Orients CD8 to a T Cell Proximal PositionPresenilin/gamma-secretase and alpha-secretase-like peptidases cleave human MHC Class I proteinsHLA-F complex without peptide binds to MHC class I protein in the open conformer form.MHC class I endosomal and lysosomal trafficking coincides with exogenous antigen loading in dendritic cellsConstitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathwayRecognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptorsNatural splice variant of MHC class I cytoplasmic tail enhances dendritic cell-induced CD8+ T-cell responses and boosts anti-tumor immunity.P2X7 receptor activation impairs exogenous MHC class I oligopeptides presentation in antigen presenting cells.Characterization of signaling function and expression of HLA class I molecules in medulloblastoma.The major histocompatibility complex and autism spectrum disorder.MHC-I molecules selectively inhibit cell-mediated cytotoxicity triggered by ITAM-coupled activating receptors and 2B4Inhibition of heavy chain and beta2-microglobulin synthesis as a mechanism of major histocompatibility complex class I downregulation during Epstein-Barr virus replicationMHCI negatively regulates synapse density during the establishment of cortical connections.BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of MelanomaCryptic protein-protein interaction motifs in the cytoplasmic domain of MHCI proteins.DC-SIGN, C1q, and gC1qR form a trimolecular receptor complex on the surface of monocyte-derived immature dendritic cellsNon-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue.Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.Divide, Conquer, and Sense: CD8+CD28- T Cells in Perspective.The Expanding Spectrum of Ligands for Leukocyte Ig-like Receptors.Intracellular recycling and cross-presentation by MHC class I molecules.Induction of HLA-B27 heavy chain homodimer formation after activation in dendritic cellsMHC molecules lead many lives. Workshop on MHC Class I Molecules at the interface between Biology & Medicine.Major histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization.Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles.Immunoproteomic analysis of the antibody response obtained in mouse following vaccination with a T-cell vaccine.The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling
P2860
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P2860
Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Misfolding of major histocompa ...... with tyrosine phosphorylation.
@en
Misfolding of major histocompa ...... with tyrosine phosphorylation.
@nl
type
label
Misfolding of major histocompa ...... with tyrosine phosphorylation.
@en
Misfolding of major histocompa ...... with tyrosine phosphorylation.
@nl
prefLabel
Misfolding of major histocompa ...... with tyrosine phosphorylation.
@en
Misfolding of major histocompa ...... with tyrosine phosphorylation.
@nl
P2860
P50
P356
P1476
Misfolding of major histocompa ...... with tyrosine phosphorylation.
@en
P2860
P304
53062-53070
P356
10.1074/JBC.M408794200
P407
P577
2004-10-07T00:00:00Z