Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.
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Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signalingPolarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domainsM1-muscarinic receptors promote fear memory consolidation via phospholipase C and the M-currentPungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channelsNeural KCNQ (Kv7) channelsElectrical resonance with voltage-gated ion channels: perspectives from biophysical mechanisms and neural electrophysiologyKCNQ potassium channels in sensory system and neural circuitsGenetic epilepsy syndromes without structural brain abnormalities: clinical features and experimental modelsIon channels as drug targets in central nervous system disordersSearching for new targets for treatment of pediatric epilepsyPremature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice.Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potentialK(V)7/KCNQ channels are functionally expressed in oligodendrocyte progenitor cellsCoordinated signal integration at the M-type potassium channel upon muscarinic stimulationContribution of KCNQ2 and KCNQ3 to the medium and slow afterhyperpolarization currentsDV21 decreases excitability of cortical pyramidal neurons and acts in epilepsy.N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of EpilepsyM-type potassium channels modulate the intrinsic excitability of infralimbic neurons and regulate fear expression and extinctionProtein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activityPathogenic plasticity of Kv7.2/3 channel activity is essential for the induction of tinnitus.KCNQ channels show conserved ethanol block and function in ethanol behaviour.Deletion of the potassium channel Kv12.2 causes hippocampal hyperexcitability and epilepsy.Extending the KCNQ2 encephalopathy spectrum: clinical and neuroimaging findings in 17 patients.Rescue of homeostatic regulation of striatal excitability and locomotor activity in a mouse model of Huntington's disease.Physiological bases of the K+ and the glutamate/GABA hypotheses of epilepsy.Neonatal nonepileptic myoclonus is a prominent clinical feature of KCNQ2 gain-of-function variants R201C and R201H.PP2A-Bgamma subunit and KCNQ2 K+ channels in bipolar disorder.Improvement of aroma in transgenic potato as a consequence of impairing tuber browning.Gain control in CA1 pyramidal cells using changes in somatic conductance.The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.Polarized axonal surface expression of neuronal KCNQ potassium channels is regulated by calmodulin interaction with KCNQ2 subunit.Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristicsActivation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats.Long-term oestradiol treatment enhances hippocampal synaptic plasticity that is dependent on muscarinic acetylcholine receptors in ovariectomised female rats.Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels.Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampusAxon physiology.The specific slow afterhyperpolarization inhibitor UCL2077 is a subtype-selective blocker of the epilepsy associated KCNQ channelsVoltage-gated potassium channels at the crossroads of neuronal function, ischemic tolerance, and neurodegeneration.
P2860
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P2860
Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Conditional transgenic suppres ...... ility, resonance and behavior.
@en
Conditional transgenic suppres ...... ility, resonance and behavior.
@nl
type
label
Conditional transgenic suppres ...... ility, resonance and behavior.
@en
Conditional transgenic suppres ...... ility, resonance and behavior.
@nl
prefLabel
Conditional transgenic suppres ...... ility, resonance and behavior.
@en
Conditional transgenic suppres ...... ility, resonance and behavior.
@nl
P2093
P356
P1433
P1476
Conditional transgenic suppres ...... bility, resonance and behavior
@en
P2093
Dirk Isbrandt
H Christian Peters
Johan F Storm
Olaf Pongs
P2888
P356
10.1038/NN1375
P407
P50
P577
2004-12-19T00:00:00Z
P5875
P6179
1008549698