Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis. - Wikidata - awgldk - TriplyDB

Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis.

Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis.

http://www.wikidata.org/entity/Q45251307

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Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection Immunomodulatory therapies for acute pancreatitis.Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching Adjudin protects against cerebral ischemia reperfusion injury by inhibition of neuroinflammation and blood-brain barrier disruption Practice guidelines in acute pancreatitis.Pancreatic stellate cells and CX3CR1: occurrence in normal pancreas and acute and chronic pancreatitis and effect of their activation by a CX3CR1 agonist Monocyte chemoattractant protein 1 regulates pulmonary host defense via neutrophil recruitment during Escherichia coli infection.Effect of mitogen-activated protein kinases on chemokine synthesis induced by substance P in mouse pancreatic acinar cells.Induction of apoptosis by crambene protects mice against acute pancreatitis via anti-inflammatory pathways.Role of chemokines in the pathogenesis of acute lung injury.The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis.Intrapulmonary G-CSF rescues neutrophil recruitment to the lung and neutrophil release to blood in Gram-negative bacterial infection in MCP-1-/- mice.Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis.Role of immune cells and immune-based therapies in pancreatitis and pancreatic ductal adenocarcinoma.An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo.Age-dependent vulnerability to experimental acute pancreatitis is associated with increased systemic inflammation and thrombosis.The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice.Role of MCP-1 in cardiovascular disease: molecular mechanisms and clinical implications.N-acetylcysteine in acute pancreatitis.Immune cells and immune-based therapy in pancreatitis.Immune-modulating therapy in acute pancreatitis: fact or fiction.Adjudin--A Male Contraceptive with Other Biological Activities.Therapeutic implications of innate immune system in acute pancreatitis.Synergy between phenotypic modulation and ROS neutralization in reduction of inflammatory response of hypoxic microglia by using phosphatidylserine and antioxidant containing liposomes.Adjudin attenuates lipopolysaccharide (LPS)- and ischemia-induced microglial activation.Targeting monocyte chemotactic protein-1 synthesis with bindarit induces tumor regression in prostate and breast cancer animal models.Pomalidomide suppresses cerulein-induced acute pancreatitis in mice.Prostaglandin E2 modulates TNF-alpha-induced MCP-1 synthesis in pancreatic acinar cells in a PKA-dependent manner.Glycyrrhizin down-regulates CCL2 and CXCL2 expression in cerulein-stimulated pancreatic acinar cells.Cystathionine-gamma-lyase gene silencing with siRNA in monocytes/macrophages protects mice against acute pancreatitis.Glycyrrhizin attenuates tissue injury and reduces neutrophil accumulation in experimental acute pancreatitis.Effect of long- and short-term treatments with pravastatin on diabetes mellitus and pancreatic fibrosis in the Otsuka-Long-Evans-Tokushima fatty rat.Inflammatory role of the acinar cells during acute pancreatitis.Essential role of monocytes and macrophages in the progression of acute pancreatitis.The chemokine monocyte chemoattractant protein-1 contributes to renal dysfunction in swine renovascular hypertension.A murine model of obesity implicates the adipokine milieu in the pathogenesis of severe acute pancreatitis.Adjudin-preconditioned neural stem cells enhance neuroprotection after ischemia reperfusion in mice.Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis.A rat model reproducing key pathological responses of alcoholic chronic pancreatitis.

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P2860

Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis.

http://www.wikidata.org/entity/Q45251307

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Treatment with bindarit, a blo ...... ce against acute pancreatitis.

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Treatment with bindarit, a blo ...... ce against acute pancreatitis.

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Angelo Guglielmotti

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Lakshmi Chevali

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Madhav Bhatia

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Raina Devi Ramnath

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P2860

Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes

Blocking pulmonary ICAM-1 expression ameliorates lung injury in established diet-induced pancreatitis

Advances in the treatment of lupus nephritis.

Inflammatory mediators in acute pancreatitis.

Novel therapeutic targets for acute pancreatitis and associated multiple organ dysfunction syndrome.

Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome.

Pathophysiology of acute pancreatitis.

Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury.

Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury.

Amelioration of rat adjuvant arthritis by therapeutic treatment with bindarit, an inhibitor of MCP-1 and TNF-alpha production.

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