Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
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Apoptotic Regulation by MCL-1 through HeterodimerizationMcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cellsSuppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction.Bortezomib-induced sensitization of malignant human glioma cells to vorinostat-induced apoptosis depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation, Mcl-1 cleavage, and DNA damage.Mcl-1 ubiquitination: unique regulation of an essential survival protein.Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis.Toxoplasma gondii inhibits granzyme B-mediated apoptosis by the inhibition of granzyme B function in host cellsInterleukin-7 inhibits tumor-induced CD27-CD28- suppressor T cells: implications for cancer immunotherapy.Combining mTor inhibitors with rapamycin-resistant T cells: a two-pronged approach to tumor elimination.Rapid turnover of mcl-1 couples translation to cell survival and apoptosis.Hypoxic switch in mitochondrial myeloid cell leukemia factor-1/Mtd apoptotic rheostat contributes to human trophoblast cell death in preeclampsia.The protein kinase C delta catalytic fragment targets Mcl-1 for degradation to trigger apoptosis.Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim.Myeloid cell leukemia-1 as a therapeutic target.Mechanisms of granule-dependent killing.Amplification of distant estrogen response elements deregulates target genes associated with tamoxifen resistance in breast cancer.Chemosensitization of prostate cancer by modulating Bcl-2 family proteins.Intersection of mitochondrial fission and fusion machinery with apoptotic pathways: Role of Mcl-1.Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.Caspase-dependent Mcl-1 cleavage and effect of Mcl-1 phosphorylation in ABT-737-induced apoptosis in human acute lymphoblastic leukemia cell lines.Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1.Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis.Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells.Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs.Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis.Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.
P2860
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P2860
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
@en
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
@nl
type
label
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
@en
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
@nl
prefLabel
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
@en
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
@nl
P2093
P2860
P356
P1476
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
@en
P2093
Asaf Rabinovitz
Brian R Gastman
Hannah Rabinowich
Leslie A Goldstein
P2860
P304
16383-16392
P356
10.1074/JBC.M411377200
P407
P577
2005-02-15T00:00:00Z