Multidrug resistance in epilepsy: rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizures.
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Unique behavioral characteristics and microRNA signatures in a drug resistant epilepsy modelDrug-Resistant Epilepsy: Multiple Hypotheses, Few AnswersDrug resistance in brain diseases and the role of drug efflux transporters.Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy.The piriform cortex and human focal epilepsy.Homeostatic bioenergetic network regulation - a novel concept to avoid pharmacoresistance in epilepsy.The role of common variation in drug transporter genes in refractory epilepsy.Genetic association studies in epilepsy pharmacogenomics: lessons learnt and potential applications.Role of oxidative stress in refractory epilepsy: evidence in patients and experimental models.Carbamazepine, but not valproate, displays pharmacoresistance in lamotrigine-resistant amygdala kindled rats.Drug transporters in the epileptic brain.Imaging of P-glycoprotein function and expression to elucidate mechanisms of pharmacoresistance in epilepsy.Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures.One of the hottest topics in epileptology: ABC proteins. Their inhibition may be the future for patients with intractable seizures.Transporter hypothesis of drug-resistant epilepsy: challenges for pharmacogenetic approaches.Blood-brain barrier P450 enzymes and multidrug transporters in drug resistance: a synergistic role in neurological diseases.Mechanisms of drug resistance in epilepsy: relevance for antiepileptic drug discovery.Pathogenetic mechanisms of focal cortical dysplasia.Intractable epilepsy and the P-glycoprotein hypothesis.The possible use of the L-type calcium channel antagonist verapamil in drug-resistant epilepsy.New developments in antiepileptic drug resistance: an integrative viewAssessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein.Targeting anti-epileptic drug therapy without collateral damage: nanocarrier-based drug delivery.Means, motive, and opportunity: establishing culpability in pharmacoresistant epilepsy.The multidrug transporter hypothesis of refractory epilepsy: corroboration and contradiction in equal measure.Role of P-glycoprotein inhibitors in children with drug-resistant epilepsy.Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs.Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy.MK-801 prevents overexpression of multidrug resistance protein 2 after status epilepticus.ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients.Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats.Correlation study on expression of GST-π protein in brain tissue and peripheral blood of epilepsy rats induced by pilocarpine.Phenytoin carried by silica core iron oxide nanoparticles reduces the expression of pharmacoresistant seizures in rats.
P2860
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P2860
Multidrug resistance in epilepsy: rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizures.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Multidrug resistance in epilep ...... with drug-responsive seizures.
@en
Multidrug resistance in epilep ...... with drug-responsive seizures.
@nl
type
label
Multidrug resistance in epilep ...... with drug-responsive seizures.
@en
Multidrug resistance in epilep ...... with drug-responsive seizures.
@nl
prefLabel
Multidrug resistance in epilep ...... with drug-responsive seizures.
@en
Multidrug resistance in epilep ...... with drug-responsive seizures.
@nl
P2860
P356
P1433
P1476
Multidrug resistance in epilep ...... with drug-responsive seizures
@en
P2093
Wolfgang Löscher
P2860
P304
P356
10.1093/BRAIN/AWH437
P407
P577
2005-02-16T00:00:00Z