From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
about
Indirubin and Indirubin Derivatives for Counteracting Proliferative DiseasesPotential of plant-derived natural products in the treatment of leukemia and lymphomaSoluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period.Purified brominated indole derivatives from Dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines.Kinetics, in silico docking, molecular dynamics, and MM-GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP-binding site inhibitors: the role of water molecules examined.Indirubin derivatives: a patent review (2010 - present).The Role of Indirubins in Inflammation and Associated Tumorigenesis.Water-soluble cationic derivatives of indirubin, the active anticancer component from Indigo naturalis.Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK.Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway.Design, Synthesis and Preliminary Antimicrobial Evaluation of N-Alkyl Chain Tethered C-5 Functionalized Bis-Isatins.Evaluating the enthalpic contribution to ligand binding using QM calculations: effect of methodology on geometries and interaction energies.
P2860
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P2860
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
@en
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
@nl
type
label
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
@en
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
@nl
prefLabel
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
@en
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
@nl
P2093
P2860
P356
P1433
P1476
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.
@en
P2093
Gerhard Siemeister
Hans Briem
Martin Krüger
Martina Schäfer
Olaf Prien
Rolf Jautelat
Stefan Schwahn
Thomas Brumby
Ulrich Lücking
P2860
P304
P356
10.1002/CBIC.200400108
P577
2005-03-01T00:00:00Z