PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington's Disease.
about
The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's diseaseIron accumulates in Huntington's disease neurons: protection by deferoxamineNeonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease.Pharmacological activity of metal binding agents that alter copper bioavailability.Oxidative Stress and Huntington's Disease: The Good, The Bad, and The Ugly.Biometals and their therapeutic implications in Alzheimer's disease.Neurotoxicity of Copper.The pharmacological perturbation of brain zinc impairs BDNF-related signaling and the cognitive performances of young mice.
P2860
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P2860
PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington's Disease.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
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2012年學術文章
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2012年學術文章
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name
PBT2 Reduces Toxicity in a C. ...... Model of Huntington's Disease.
@en
PBT2 Reduces Toxicity in a C. ...... Model of Huntington's Disease.
@nl
type
label
PBT2 Reduces Toxicity in a C. ...... Model of Huntington's Disease.
@en
PBT2 Reduces Toxicity in a C. ...... Model of Huntington's Disease.
@nl
prefLabel
PBT2 Reduces Toxicity in a C. ...... Model of Huntington's Disease.
@en
PBT2 Reduces Toxicity in a C. ...... Model of Huntington's Disease.
@nl
P2093
P50
P921
P356
P1476
PBT2 Reduces Toxicity in a C. ...... Model of Huntington's Disease.
@en
P2093
David I Finkelstein
Robert A Cherny
Stephen M Massa
P304
P356
10.3233/JHD-120029
P577
2012-01-01T00:00:00Z