about
PI4P is phosphorylated to PI(4;5)P2 by PIP5K1A-C at the plasma membranePI(4;5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membranePI(4;5)P2 is phosphorylated to PI(3;4;5)P3 by PIK3C[1] at the plasma membranePI(3;4)P2 is phosphorylated to PI(3;4;5)P3 by PIP5K1A-C at the plasma membranePI(3;4;5)P3 is dephosphorylated to PI(3;4)P2 by INPP5[2] at the plasma membranePI4P is phosphorylated to PI(3;4)P2 by PI3K3C[2] at the plasma membranePI(3;4)P2 is dephosphorylated to PI4P by PTEN at the plasma membranePI3P is phosphorylated to PI(3;4)P2 by PIP4K2/5K1 at the plasma membranePI(3;4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membranePI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membranePTPN13:PLEKHA1;2 bind PI(3;4)P2PLEKHA3;8 bind PI4P; ARF1PLEKHA4;(5;6) bind PI3PMTMR6 binds MTMR9MTMR8 binds MTMR9PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membranePI is phosphorylated to PI5P by PIP5K1A/B at the plasma membranePI3P is phosphorylated to PI(3;5)P2 by PIP5K1A/B at the plasma membranePI(3;5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membranePI(3;5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membranePI(3;5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membranePI5P is phosphorylated to PI(4;5)P2 by PIP4K2 dimers at the plasma membranePI is phosphorylated to PI4P by PI4K2A/B at the plasma membranePI4P is dephosphorylated to PI by SYNJ at the plasma membraneMTMR2 dimerizesMTMR2 binds SBF2PI(3;5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membranePI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membraneBMX phosphorylates RUFY1p-Y281;292-RUFY1 translocates from cytosol to early endosome membranep-Y281;292-RUFY1 binds PI3Pp-Y281;292-RUFY1 binds RAB4A:GTP; RAB5:GTP; RAB14:GTP
P361
P527
Q50293917-988E4BC8-FEA4-4D78-B330-38BCB3893D49Q50293918-C0088FE5-6494-401D-8AB4-672726ABD10EQ50293919-D3FF3501-6D4E-49F8-B1CC-AFD71C4CD325Q50293920-EF6272EA-6E22-4E19-8D03-8CE23252F7CDQ50293921-3795F997-5210-4057-9EFD-845E8FAD3A34Q50293923-1D88BE4B-3DDF-4C8B-AFF8-6003CF91402AQ50293924-AF5F2203-3D4B-4DD7-8FAD-62DEF1925C26Q50293925-1A998C02-0E64-4184-A419-0DE6BBA6AD50Q50293926-CBA43B65-7CD9-4DFD-99EA-584BAE498B10Q50293927-FA965A02-4169-48B6-A871-9768A03E29DAQ50293928-FD806D02-BE0C-4A33-A4D9-D35D4B3A7916Q50293929-13BA5639-F431-4D63-B71A-DC4851977425Q50293930-4470E5B6-6DA9-4C20-801B-F3327DB20971Q50293931-FF1CA47B-6C8E-413C-B5D4-758CD3DB981FQ50293932-D0F4FFD9-8ADC-40B0-A1E7-4B95201BDCD0Q50293933-5314396A-8FC0-4071-8FA4-BAEACF837883Q50293934-7E938455-AD2C-4FE7-92A3-86D91A3B19B4Q50293935-A1554E69-741C-49E7-BAC0-BF08293F99B4Q50293936-97DE7EBC-404E-4127-9637-B9E80F2E58BEQ50293937-E290A571-4C68-4C23-A4E1-CF190094C5EEQ50293938-2998CBDE-07D2-4CB7-997F-9D8C5C730160Q50293940-04EDFEAE-6894-4599-91FB-03FD86A8E509Q50293942-B172A9BE-CE29-4678-A691-5BA5888E784DQ50293943-204B1CC2-F855-4474-B0ED-531606AE7353Q50293944-BC3CCB25-444A-4AF1-BD0C-2837C07F8C57Q50293945-4383E987-8FBB-4315-B985-B878D87F881BQ50293946-D8DEC716-2F84-49B6-B45B-E97F5F392A97Q50293948-A2F01259-5EEE-41B6-810C-FB56F24DCBC2Q50293949-B39AFAF4-6B4C-404F-BF08-207A7172D8CAQ50293950-FCF78DE1-9A4D-442E-BDE7-F752509C02BFQ50293951-8212C31A-5848-4795-8E0D-5244924E9063Q50293952-463D036A-3A47-4962-9A8A-DC9FE9332C69
P361
description
An instance of the biological ...... lasma membrane in Homo sapiens
@en
name
Synthesis of PIPs at the plasma membrane
@en
type
label
Synthesis of PIPs at the plasma membrane
@en
prefLabel
Synthesis of PIPs at the plasma membrane
@en
P2860
P527
P2860
P361
P3937
R-HSA-1660499