Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier. - Wikidata - awgldk - TriplyDB

Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier.

Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier.

http://www.wikidata.org/entity/Q45560504

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Myxoma virus M-T5 protects infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1 Replication of subgenomic hepatitis C virus replicons in mouse fibroblasts is facilitated by deletion of interferon regulatory factor 3 and expression of liver-specific microRNA 122 Immunomodulatory functions of type I interferons Cytokine synergy: an underappreciated contributor to innate anti-viral immunity Oncolytic virus therapy for glioblastoma multiforme: concepts and candidates Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival Resistance to Alpha/Beta Interferon Is a Determinant of West Nile Virus Replication Fitness and Virulence The Marmoset Model of GB Virus B Infections: Adaptation to Host Phenotypic Variation Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication Up-Regulation of Hepatitis C Virus Replication and Production by Inhibition of MEK/ERK Signaling Poxvirus tropism Pathogenesis of noroviruses, emerging RNA viruses Myxoma virus oncolytic efficiency can be enhanced through chemical or genetic disruption of the actin cytoskeleton RIG-I mediates the co-induction of tumor necrosis factor and type I interferon elicited by myxoma virus in primary human macrophages Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro and further improved by hyaluronan in vivo.Oncolytic viral purging of leukemic hematopoietic stem and progenitor cells with Myxoma virus Mechanisms of severe acute respiratory syndrome pathogenesis and innate immunomodulation.Macroevolutionary Immunology: A Role for Immunity in the Diversification of Animal life.Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain Barriers of hepatitis C virus interspecies transmission Dengue virus serotype 2 blocks extracellular signal-regulated kinase and nuclear factor-κB activation to downregulate cytokine production.Genetic Dissection of the Host Tropism of Human-Tropic Pathogens.A whole-genome RNA interference screen for human cell factors affecting myxoma virus replication Highly pathogenic H5N1 influenza A virus strains provoke heterogeneous IFN-α/β responses that distinctively affect viral propagation in human cells.Resistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent of anti-viral type-I interferon.Poxviral regulation of the host NF-kappaB response: the vaccinia virus M2L protein inhibits induction of NF-kappaB activation via an ERK2 pathway in virus-infected human embryonic kidney cells.Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas.Myxoma virus oncolysis of primary and metastatic B16F10 mouse tumors in vivo.Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.Histological evaluation of intratumoral myxoma virus treatment in an immunocompetent mouse model of melanoma.M135R is a novel cell surface virulence factor of myxoma virus Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells.A vaccinia virus-driven interplay between the MKK4/7-JNK1/2 pathway and cytoskeleton reorganization NS1 proteins of avian influenza A viruses can act as antagonists of the human alpha/beta interferon response.The vaccinia virus O1 protein is required for sustained activation of extracellular signal-regulated kinase 1/2 and promotes viral virulence.The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases.The potential role of fowlpox virus in rational vaccine design.Vesicular stomatitis virus oncolysis of T lymphocytes requires cell cycle entry and translation initiation.Strategies to achieve systemic delivery of therapeutic cells and microbes to tumors.Viruses as anticancer drugs.

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P2860

Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier.

http://www.wikidata.org/entity/Q45560504

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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name

Disruption of Erk-dependent ty ...... myxoma virus species barrier.

@en

Disruption of Erk-dependent ty ...... myxoma virus species barrier.

@nl

type

label

Disruption of Erk-dependent ty ...... myxoma virus species barrier.

@en

Disruption of Erk-dependent ty ...... myxoma virus species barrier.

@nl

prefLabel

Disruption of Erk-dependent ty ...... myxoma virus species barrier.

@en

Disruption of Erk-dependent ty ...... myxoma virus species barrier.

@nl

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Nature Immunology

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Disruption of Erk-dependent ty ...... myxoma virus species barrier.

@en

P2093

Erik Barton

http://www.w3.org/2001/XMLSchema#string

Fuan Wang

http://www.w3.org/2001/XMLSchema#string

John W Barrett

http://www.w3.org/2001/XMLSchema#string

Joy Loh

http://www.w3.org/2001/XMLSchema#string

Xiujuan Gao

http://www.w3.org/2001/XMLSchema#string

Yiyue Ma

http://www.w3.org/2001/XMLSchema#string

P2860

Use of chemokine receptors by poxviruses

Functional role of type I and type II interferons in antiviral defense

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

Antiviral actions of interferons

How cells respond to interferons

Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade.

PKR; a sentinel kinase for cellular stress

IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

Triggering the interferon antiviral response through an IKK-related pathway

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1266-1274

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scholarly article

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10.1038/NI1132

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12

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5

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Herbert W. "Skip" Virgin

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2004-10-24T00:00:00Z

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15502830

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