Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
about
The emerging field of RNA nanotechnologyCurrent advances in Phi29 pRNA biology and its application in drug deliveryCrystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNAControllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnologyConstruction of bacteriophage phi29 DNA packaging motor and its applications in nanotechnology and therapyRNA nanotechnology: engineering, assembly and applications in detection, gene delivery and therapyFabrication of stable and RNase-resistant RNA nanoparticles active in gearing the nanomotors for viral DNA packaging.Understanding the effects of carbocyclic sugars constrained to north and south conformations on RNA nanodesignPharmacological characterization of chemically synthesized monomeric phi29 pRNA nanoparticles for systemic delivery.Counting of six pRNAs of phi29 DNA-packaging motor with customized single-molecule dual-view system.Gene therapy of liver diseases.Uniqueness, advantages, challenges, solutions, and perspectives in therapeutics applying RNA nanotechnology.Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers.Fluorogenic RNA nanoparticles for monitoring RNA folding and degradation in real time in living cells.RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applicationsRNA nanotechnology for computer design and in vivo computation.Reversible switching of pRNA activity on the DNA packaging motor of bacteriophage phi29.Fabrication of pRNA nanoparticles to deliver therapeutic RNAs and bioactive compounds into tumor cells.Programmable folding of fusion RNA in vivo and in vitro driven by pRNA 3WJ motif of phi29 DNA packaging motor.Stable RNA nanoparticles as potential new generation drugs for cancer therapy.Hairpin Ribozyme Genes Curtail Alcohol Drinking: from Rational Design to in vivo Effects in the RatEngineering RNA for targeted siRNA delivery and medical application.Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cellsNucleic acid-based nanoengineering: novel structures for biomedical applications.Ultrastable pRNA hexameric ring gearing hexameric phi29 DNA-packaging motor by revolving without rotating and coiling.Gene therapeutic approaches to inhibit hepatitis B virus replication.Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics.Elastic properties and heterogeneous stiffness of the phi29 motor connector channel.Specific Delivery of MiRNA for High Efficient Inhibition of Prostate Cancer by RNA Nanotechnology.RNA as a boiling-resistant anionic polymer material to build robust structures with defined shape and stoichiometry.Entropy-driven one-step formation of Phi29 pRNA 3WJ from three RNA fragments.Advancement of the Emerging Field of RNA Nanotechnology.Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs.Assembly of therapeutic pRNA-siRNA nanoparticles using bipartite approach.Specific delivery of therapeutic RNAs to cancer cells via the dimerization mechanism of phi29 motor pRNA.Construction of folate-conjugated pRNA of bacteriophage phi29 DNA packaging motor for delivery of chimeric siRNA to nasopharyngeal carcinoma cells.Evaluation of specific delivery of chimeric phi29 pRNA/siRNA nanoparticles to multiple tumor cells.Phi29 Connector-DNA Interactions Govern DNA Crunching and Rotation, Supporting the Check-Valve Model.Mechanism of three-component collision to produce ultrastable pRNA three-way junction of Phi29 DNA-packaging motor by kinetic assessment.Controllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting.
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Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
@en
Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
@nl
type
label
Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
@en
Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
@nl
prefLabel
Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
@en
Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
@nl
P2093
P2860
P356
P1433
P1476
Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus.
@en
P2093
Hoeprich S
P2860
P2888
P304
P356
10.1038/SJ.GT.3302002
P577
2003-08-01T00:00:00Z
P5875
P6179
1014423097