Amyloid deposition and influx transporter expression at the blood-brain barrier increase in normal aging. - Wikidata - awgldk - TriplyDB

Amyloid deposition and influx transporter expression at the blood-brain barrier increase in normal aging.

Amyloid deposition and influx transporter expression at the blood-brain barrier increase in normal aging.

http://www.wikidata.org/entity/Q45776839

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Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1 Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-β is an early biomarker for mild cognitive impairment preceding Alzheimer's disease Enhanced Chemokine Receptor Expression on Leukocytes of Patients with Alzheimer's Disease Amyloid-beta transporter expression at the blood-CSF barrier is age-dependent.Temporal course of cerebrospinal fluid dynamics and amyloid accumulation in the aging rat brain from three to thirty months.Low-density lipoprotein receptor-related protein 1: a physiological Aβ homeostatic mechanism with multiple therapeutic opportunities.Amyloid plaque pathogenesis in 5XFAD mouse spinal cord: retrograde transneuronal modulation after peripheral nerve injury Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease Increased expression of the receptor for advanced glycation end products in neurons and astrocytes in a triple transgenic mouse model of Alzheimer's disease.The distributional nexus of choroid plexus to cerebrospinal fluid, ependyma and brain: toxicologic/pathologic phenomena, periventricular destabilization, and lesion spread.Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype.Road to Alzheimer's disease: the pathomechanism underlying.Is RAGE still a therapeutic target for Alzheimer's disease?Metallostasis and amyloid β-degrading enzymes.Drug access to the central nervous system in Alzheimer's disease: preclinical and clinical insights.Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD).In vitro and in vivo characterization of several functionalized ultrasmall particles of iron oxide, vectorized against amyloid plaques and potentially able to cross the blood-brain barrier: toward earlier diagnosis of Alzheimer's disease by molecula Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer's Disease.Fast circulation of cerebrospinal fluid: an alternative perspective on the protective role of high intracranial pressure in ocular hypertension.The effect of aging on brain barriers and the consequences for Alzheimer's disease development.EGb761 provides a protective effect against Aβ1-42 oligomer-induced cell damage and blood-brain barrier disruption in an in vitro bEnd.3 endothelial model Sex Hormone Decline and Amyloid β Synthesis, Transport and Clearance in the Brain.Aging of cerebral white matter.Glial markers and emotional memory in rats following acute cerebral radiofrequency exposures.The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer's disease.Kaolin-induced chronic hydrocephalus accelerates amyloid deposition and vascular disease in transgenic rats expressing high levels of human APP.Potential therapeutic system for Alzheimer's disease: removal of blood Aβs by hemodialzyers and its effect on the cognitive functions of renal-failure patients.Endothelial LRP1 - A Potential Target for the Treatment of Alzheimer's Disease : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla.Diversity of astroglial responses across human neurodegenerative disorders and brain aging.The blood brain barrier: Insights from development and ageing.Aging alters mRNA expression of amyloid transporter genes at the blood-brain barrier.Regional Gene Expression of Inflammation and Oxidative Stress Responses Does Not Predict Neurodegeneration in Aging.Genes involved in cerebrospinal fluid production as candidate genes for late-onset Alzheimer's disease: a hypothesis.A prospective study on blood Aβ levels and the cognitive function of patients with hemodialysis: a potential therapeutic strategy for Alzheimer's disease.Reduction of Alzheimer's disease amyloid-β in plasma by hemodialysis and its relation to cognitive functions.Amyloid efflux transporter expression at the blood-brain barrier declines in normal aging.Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood-brain barrier

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P2860

Amyloid deposition and influx transporter expression at the blood-brain barrier increase in normal aging.

http://www.wikidata.org/entity/Q45776839

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

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2010年學術文章

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2010年學術文章

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name

Amyloid deposition and influx ...... rier increase in normal aging.

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Amyloid deposition and influx ...... rier increase in normal aging.

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type

label

Amyloid deposition and influx ...... rier increase in normal aging.

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Amyloid deposition and influx ...... rier increase in normal aging.

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prefLabel

Amyloid deposition and influx ...... rier increase in normal aging.

@en

Amyloid deposition and influx ...... rier increase in normal aging.

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NEN.0B013E3181C8AD2F

P1433

Journal of Neuropathology & Experimental Neurology

P1476

Amyloid deposition and influx ...... rier increase in normal aging.

@en

P2093

Arthur A Messier

http://www.w3.org/2001/XMLSchema#string

Edward G Stopa

http://www.w3.org/2001/XMLSchema#string

Gerald D Silverberg

http://www.w3.org/2001/XMLSchema#string

John E Donahue

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Miles C Miller

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Samir Majmudar

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P2860

Role of the Blood-Brain Barrier in the Pathogenesis of Alzheimers Disease

S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains

Neuropathological stageing of Alzheimer-related changes

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

Ageing choroid plexus-cerebrospinal fluid system.

Gene regulation and DNA damage in the ageing human brain.

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98-108

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scholarly article

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10.1097/NEN.0B013E3181C8AD2F

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1

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69

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Jason T. Machan

Conrad Johanson

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2010-01-01T00:00:00Z

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20010299

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P921

blood–brain barrier