Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor.
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cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF moleculesIsolation and chromosomal localization of the human fgr protooncogene, a distinct member of the tyrosine kinase gene familyIndependent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathwaysStructural and functional studies on platelet-derived growth factorIncreased platelet-derived growth factor A-chain expression in human uterine smooth muscle cells during the physiologic hypertrophy of pregnancyNucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factorStructural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteinsUpdate on HER-2 as a target for cancer therapy: alternative strategies for targeting the epidermal growth factor system in cancerPurification of storage granule protein-23. A novel protein identified by phage display technology and interaction with type I plasminogen activator inhibitorPDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularlyPlatelet-derived growth factor. Three isoforms that bind to two distinct cell surface receptorsStructural and functional aspects of platelet-derived growth factorConnective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation.Aberrant expression of receptors for platelet-derived growth factor in an anaplastic thyroid carcinoma cell line.Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein.The B chain of PDGF alone is sufficient for mitogenesis.Acute lung injury. Pathogenesis of intraalveolar fibrosis.Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance.Platelet-derived growth factor. Structure, function, and roles in normal and transformed cells.Ultrastructural localization of a platelet-derived growth factor/v-sis-related protein(s) in cytoplasm and nucleus of simian sarcoma virus-transformed cells.Expression of platelet-derived growth factor (PDGF)-related transcripts and synthesis of biologically active PDGF-like proteins by human malignant epithelial cell lines.Identification of processing events in the synthesis of platelet-derived growth factor-like proteins by human osteosarcoma cells.Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages.Cultured human endothelial cells express platelet-derived growth factor A chain.Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BBCell surface expression of membrane-anchored v-sis gene products: glycosylation is not required for cell surface transportIsolation and sequencing of a cDNA clone homologous to the v-sis oncogene from human endothelial cells.A small v-sis/platelet-derived growth factor (PDGF) B-protein domain in which subtle conformational changes abrogate PDGF receptor interaction and transforming activity.Inducible overexpression and secretion of int-1 protein.Identification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factorPartially transformed, anchorage-independent human diploid fibroblasts result from overexpression of the c-sis oncogene: mitogenic activity of an apparent monomeric platelet-derived growth factor 2 species.Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects.Expression and purification of biologically active v-sis/platelet-derived growth factor B protein by using a baculovirus vector system.Deletions in the N-terminal coding region of the v-sis gene: determination of the minimal transforming regionp59v-rel, the transforming protein of reticuloendotheliosis virus, is complexed with at least four other proteins in transformed chicken lymphoid cells.Malignant transformation and tumor promoter treatment increase levels of a transcript for a secreted glycoproteinDifferential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factorDeletions in the C-terminal coding region of the v-sis gene: dimerization is required for transformation.
P2860
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P2860
Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor.
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年学术文章
@wuu
1983年学术文章
@zh
1983年学术文章
@zh-cn
1983年学术文章
@zh-hans
1983年学术文章
@zh-my
1983年学术文章
@zh-sg
1983年學術文章
@yue
1983年學術文章
@zh-hant
name
Structural and immunological similarities between simian sarcoma virus gene product
@nl
Structural and immunological s ...... latelet-derived growth factor.
@en
type
label
Structural and immunological similarities between simian sarcoma virus gene product
@nl
Structural and immunological s ...... latelet-derived growth factor.
@en
prefLabel
Structural and immunological similarities between simian sarcoma virus gene product
@nl
Structural and immunological s ...... latelet-derived growth factor.
@en
P2093
P356
P1433
P1476
Structural and immunological s ...... latelet-derived growth factor.
@en
P2093
Aaronson SA
Antoniades HN
Hunkapiller MW
Robbins KC
P2888
P304
P356
10.1038/305605A0
P407
P577
1983-10-01T00:00:00Z
P6179
1043416987