Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds.
about
Structure and mechanism of the M2 proton channel of influenza A virusFunctional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channelIon channel activity of influenza A virus M2 protein: characterization of the amantadine blockEmerging Roles of Viroporins Encoded by DNA Viruses: Novel Targets for Antivirals?Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomainStructure of the transmembrane region of the M2 protein H+ channelThe influenza A virus M2 cytoplasmic tail is required for infectious virus production and efficient genome packagingMechanism for proton conduction of the M(2) ion channel of influenza A virusThe gate of the influenza virus M2 proton channel is formed by a single tryptophan residueChemical rescue of histidine selectivity filter mutants of the M2 ion channel of influenza A virusInfluenza M2 proton channelsThe ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatusInfluenza A virus M2 ion channel protein: a structure-function analysisInfluenza virus-like particles containing M2 induce broadly cross protective immunityThe Influenza M2 Ectodomain Regulates the Conformational Equilibria of the Transmembrane Proton Channel: Insights from Solid-State Nuclear Magnetic ResonanceConserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine developmentCharacterization of the 1918 "Spanish" influenza virus matrix gene segmentUniversal influenza vaccines, a dream to be realized soon.Immunogenicity and protective efficacy of recombinant M2e.Hsp70c (Hsp70(359-610)) fusion protein against influenza virus infection in mice.Prediction of the structures of helical membrane proteins based on a minimum unfavorable contacts approach.Evolution of the M gene of the influenza A virus in different host species: large-scale sequence analysis.An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses.Assembly of the m2 tetramer is strongly modulated by lipid chain length.Influenza A viruses: why focusing on M2e-based universal vaccines.Consensus M2e peptide conjugated to gold nanoparticles confers protection against H1N1, H3N2 and H5N1 influenza A viruses.Targets for the induction of protective immunity against influenza a viruses.Sublingual immunization with M2-based vaccine induces broad protective immunity against influenza.A method for determining transmembrane protein structure.Solid state NMR strategy for characterizing native membrane protein structuresConformational analysis of the full-length M2 protein of the influenza A virus using solid-state NMR.Uniformity, ideality, and hydrogen bonds in transmembrane alpha-helices.Why bound amantadine fails to inhibit proton conductance according to simulations of the drug-resistant influenza A M2 (S31N).The influenza m2 cytoplasmic tail changes the proton-exchange equilibria and the backbone conformation of the transmembrane histidine residue to facilitate proton conductionSolid-state NMR characterization of conformational plasticity within the transmembrane domain of the influenza A M2 proton channel.Free-energy profiles for ions in the influenza M2-TMD channelConformational heterogeneity of the M2 proton channel and a structural model for channel activationViral ion channels: molecular modeling and simulation.Prophylactic and therapeutic activity of fully human monoclonal antibodies directed against influenza A M2 protein.How cells tune viral mechanics--insights from biophysical measurements of influenza virus.The M2 ectodomain is important for its incorporation into influenza A virions.
P2860
Q24625464-D0C22051-4AEC-45ED-88D7-51AA5971E959Q24651543-822663CD-D041-4A60-AE33-AF6A0364F199Q24655972-F99858AB-F28B-45B8-A7DC-79990F936198Q26778969-B72040CF-4FB2-412B-B3A5-A20912B11CD2Q27341132-F027686C-9788-4693-A453-24989E59BE57Q27635441-F4A11853-F267-40EE-B127-0ABF1B84DEA6Q27863808-353215E3-5220-4547-8538-EB4F7106EFBEQ28139014-72DF0308-5A54-496E-B6CC-C81AD1368C9FQ28218385-0388C179-4227-41A2-8B5A-955C0C074344Q28241293-BF4B9AE3-F0A2-4E6F-A0C3-FFD5285F7389Q28281767-A1502ECC-F1C8-40C5-A5B8-749FCCF3020AQ28282474-F3E8F93B-DC39-4DC1-8270-2F84294DCFBAQ28285692-461F8911-9AAC-49BB-AA80-BDA81C904240Q28743472-249C2584-2841-414C-B51F-2097E909F2AAQ28818506-6E069E59-36C7-40F8-B53D-AECD58816A75Q30226873-60BDF226-5029-43DD-834F-7AD5B0ED3920Q30332027-962546FD-8EF1-4878-92AA-968E0341389BQ30361950-7486EF4C-BFC9-4350-8161-65262ABE9960Q30366089-63D3CA4A-E559-4FB5-9039-CB9C8203EF70Q30370486-3A58034E-E2F1-4575-8714-B00717D66E22Q30377641-5112D0B2-C6DE-40B1-AEBC-B0BAAD3DA772Q30384563-5013D98D-5920-42AC-B89C-F7D73999C944Q30393949-29B65347-2369-45A3-9621-565413F63CBEQ30396318-4B0B06EB-88C6-4E32-92B7-3300B4974E08Q30398228-2B5DD286-0E0A-4B73-B45E-8E4AA977DB67Q30408100-5E01EFA3-F0B9-47D2-996A-8533FECB6ED8Q30410241-12ED1482-D403-41D3-B0FF-723C2022143BQ30427252-95F13C45-82A4-4330-9FB6-55DEE0D31E45Q30427981-5A6C90C6-DF50-4084-A198-90A9E2FB478FQ30666144-0577C4AC-A163-4690-8E09-39920B97BFB9Q30731658-5A0974CA-FFFD-4335-8A6A-306427307ABAQ30872106-F91DED6B-BB73-4AAF-A984-7401403C7D46Q30936825-5B176507-5F89-41C6-B680-C48D8F522273Q31133095-E6421EEF-19CD-4E84-9C7E-4C7A77344F61Q33419441-8ADD4279-4337-494C-9231-348CBEF0D295Q33487093-A8EC8757-6C57-49AD-94AC-7B7D5CC22AD0Q33536851-A3674940-0AA5-476E-AC69-36FE38659FFFQ33582945-16883B79-7618-4C62-94D7-417BD6199E12Q33736593-C4E8D807-9D54-49BF-A4EC-3A2D40A13216Q33782503-2781054E-7F7B-4C5B-A40F-A275F67ED410
P2860
Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
Influenza virus M2 integral me ...... formation of disulfide bonds.
@en
Influenza virus M2 integral me ...... formation of disulfide bonds.
@nl
type
label
Influenza virus M2 integral me ...... formation of disulfide bonds.
@en
Influenza virus M2 integral me ...... formation of disulfide bonds.
@nl
prefLabel
Influenza virus M2 integral me ...... formation of disulfide bonds.
@en
Influenza virus M2 integral me ...... formation of disulfide bonds.
@nl
P1433
P1476
Influenza virus M2 integral me ...... formation of disulfide bonds.
@en
P2093
P356
10.1016/0042-6822(91)90115-R
P407
P577
1991-07-01T00:00:00Z