Functional repair of human donor lungs by IL-10 gene therapy. - Wikidata - awgldk - TriplyDB

Functional repair of human donor lungs by IL-10 gene therapy.

Functional repair of human donor lungs by IL-10 gene therapy.

http://www.wikidata.org/entity/Q45858165

about

An important role for autoimmunity in the immunopathogenesis of chronic allograft rejection Animal models of ex vivo lung perfusion as a platform for transplantation research Overview of clinical lung transplantation Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop.Central memory CD8+ T lymphocytes mediate lung allograft acceptance.The HMGB1-RAGE axis mediates traumatic brain injury-induced pulmonary dysfunction in lung transplantation.Organomatics and organometrics: Novel platforms for long-term whole-organ culture.A physiologic and biochemical profile of clinically rejected lungs on a normothermic ex vivo lung perfusion platform.Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs Interleukin-10 repletion suppresses pro-inflammatory cytokines and decreases liver pathology without altering viral replication in murine cytomegalovirus (MCMV)-infected IL-10 knockout mice.Lung transplantation from donors after circulatory death using portable ex vivo lung perfusion Virally expressed interleukin-10 ameliorates acute encephalomyelitis and chronic demyelination in coronavirus-infected mice.Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre- and post-lung transplantation in the pig.Design and validation of a clinical-scale bioreactor for long-term isolated lung culture.Inflammatory signalling associated with brain dead organ donation: from brain injury to brain stem death and posttransplant ischaemia reperfusion injury.Primary graft dysfunction.Two-photon microscopy in pulmonary research.Molecular evolution of human species D adenoviruses.The clinical potential of ex vivo lung perfusion.Role of antibodies to self-antigens in chronic allograft rejection: potential mechanism and therapeutic implications.Clinical year in review I: quality improvement for pulmonary and critical care medicine, lung transplantation, rehabilitation for pulmonary and critically ill patients, and sleep medicine.Ex vivo lung reconditioning: a new era for lung transplantation.Expert opinion in biological therapy: update on developments in lung gene transfer.Acute respiratory distress syndrome: new definition, current and future therapeutic options Machine perfusion in solid organ transplantation: where is the benefit?Ex-vivo lung perfusion.Lung xenotransplantation: recent progress and current status.Uncontrolled Donation After Circulatory Determination of Death Donors (uDCDDs) as a Source of Lungs for Transplant.The promise of organ and tissue preservation to transform medicine.Lung xenotransplantation: a review Protein biomarkers associated with primary graft dysfunction following lung transplantation.Successful emergent lung transplantation after remote ex vivo perfusion optimization and transportation of donor lungs.Multiorgan procurement increases systemic inflammation in brain dead donors.The effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death.Multipotent adult progenitor cells decrease cold ischemic injury in ex vivo perfused human lungs: an initial pilot and feasibility study.Impact of cytokine expression in the pre-implanted donor lung on the development of chronic lung allograft dysfunction subtypes.Lentivirus IL-10 gene therapy down-regulates IL-17 and attenuates mouse orthotopic lung allograft rejection.Pharmacologic Protection of Mitochondrial DNA Integrity May Afford a New Strategy for Suppressing Lung Ischemia-Reperfusion Injury.An experimental study of the recovery of injured porcine lungs with prolonged normothermic cellular ex vivo lung perfusion following donation after circulatory death.Subnormothermic ex vivo liver perfusion is a safe alternative to cold static storage for preserving standard criteria grafts.

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Functional repair of human donor lungs by IL-10 gene therapy.

http://www.wikidata.org/entity/Q45858165

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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name

Functional repair of human donor lungs by IL-10 gene therapy.

@en

Functional repair of human donor lungs by IL-10 gene therapy.

@nl

type

label

Functional repair of human donor lungs by IL-10 gene therapy.

@en

Functional repair of human donor lungs by IL-10 gene therapy.

@nl

prefLabel

Functional repair of human donor lungs by IL-10 gene therapy.

@en

Functional repair of human donor lungs by IL-10 gene therapy.

@nl

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SCITRANSLMED.3000266

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Science Translational Medicine

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Functional repair of human donor lungs by IL-10 gene therapy

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Beverly L Davidson

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Jeffrey Medin

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Masaaki Sato

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Masaki Anraku

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Matt Rubacha

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Shaf Keshavjee

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Shin Hirayama

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Thomas K Waddell

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P2860

Interleukin-10 and the interleukin-10 receptor

The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

Junctional complexes in various epithelia

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

Proinflammatory response of alveolar epithelial cells is enhanced by alveolar macrophage-produced TNF-alpha during pulmonary ischemia-reperfusion injury.

S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.

Regulation of airway tight junctions by proinflammatory cytokines.

Ischemia-reperfusion-induced lung injury.

A review of lung transplant donor acceptability criteria.

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10.1126/SCITRANSLMED.3000266

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4

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1

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Jonathan C Yeung

Arthur S Slutsky

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43023141

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