Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.
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Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) miceEmerging role of chemokine CC motif ligand 4 related mechanisms in diabetes mellitus and cardiovascular disease: friends or foes?The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse model.Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentationAutoantigens plus interleukin-10 suppress diabetes autoimmunity.Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.Regulatory T cells in experimental autoimmune disease.Anti-inflammatory effects of probiotic yogurt in inflammatory bowel disease patients.Genetic vaccination for re-establishing T-cell tolerance in type 1 diabetes.Interleukin-10+ regulatory B cells arise within antigen-experienced CD40+ B cells to maintain tolerance to islet autoantigensNOD dendritic cells stimulated with Lactobacilli preferentially produce IL-10 versus IL-12 and decrease diabetes incidencePrevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets.The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsisRole of autoimmunity in organ allograft rejection: a focus on immunity to type V collagen in the pathogenesis of lung transplant rejection.Regulatory T-cells in type 1 diabetes.Gene therapy progress and prospects: gene therapy for diabetes mellitus.Antigen-specific induction of regulatory T cells for type 1 diabetes therapy.Sensitization to gliadin induces moderate enteropathy and insulitis in nonobese diabetic-DQ8 mice.CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion.Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 productionTreatment of human disease by adeno-associated viral gene transfer.Regulatory T cells in the periphery.Natural and induced regulatory T cells: targets for immunotherapy of autoimmune disease and allergy.Treg in type 1 diabetes.Type 1 diabetes genetic susceptibility and dendritic cell function: potential targets for treatment.Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice.Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats.Inducing immune tolerance: a focus on Type 1 diabetes mellitus.Regulation of type 1 diabetes, tuberculosis, and asthma by parasitesTh17 cells in immunity and autoimmunity.Immunomodulatory Effects of Taiwanese Neolitsea Species on Th1 and Th2 Functionality.Identification of adeno-associated viral vectors suitable for intestinal gene delivery and modulation of experimental colitis.TGFbeta plasmid construction and delivery for the prevention of type 1 diabetes.Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs.CD4(+) CD25(+) T cells prevent arthritis associated with Borrelia vaccination and infectionImmune deviation by mucosal antigen administration suppresses gene-transfer-induced inhibitor formation to factor IX.Prophylactic immune tolerance induced by changing the ratio of antigen-specific effector to regulatory T cells.Resting B cells expand a CD4+CD25+Foxp3+ Treg population via TGF-beta3.Effects of CD4(+)CD25(+)Foxp3(+)regulatory T cells on early Plasmodium yoelii 17XL infection in BALB/c mice.Freeze-thaw increases adeno-associated virus transduction of cells.
P2860
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P2860
Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Systemic overexpression of IL- ...... e in a dose-dependent fashion.
@en
Systemic overexpression of IL- ...... e in a dose-dependent fashion.
@nl
type
label
Systemic overexpression of IL- ...... e in a dose-dependent fashion.
@en
Systemic overexpression of IL- ...... e in a dose-dependent fashion.
@nl
prefLabel
Systemic overexpression of IL- ...... e in a dose-dependent fashion.
@en
Systemic overexpression of IL- ...... e in a dose-dependent fashion.
@nl
P2093
P1476
Systemic overexpression of IL- ...... e in a dose-dependent fashion.
@en
P2093
Brant R Burkhardt
Clive Wasserfall
Eric S Sobel
Kevin S Goudy
Mark A Atkinson
Matthew A Powers
Michael J Clare-Salzler
Sihong Song
Tamir M Ellis
Terence R Flotte
P304
P356
10.4049/JIMMUNOL.171.5.2270
P407
P577
2003-09-01T00:00:00Z