Muscle as a target for supplementary factor IX gene transfer.
about
Animal models of hemophiliaProgress and prospects: immune responses to viral vectorsTolerance induction to cytoplasmic beta-galactosidase by hepatic AAV gene transfer: implications for antigen presentation and immunotoxicityHepatic gene transfer as a means of tolerance induction to transgene productsBALB/c mice show impaired hepatic tolerogenic response following AAV gene transfer to the liver.Development of Gene Transfer for Induction of Antigen-specific Tolerance.Enhanced efficacy from gene therapy in Pompe disease using coreceptor blockademiRNA-mediated silencing in hepatocytes can increase adaptive immune responses to adenovirus vector-delivered transgenic antigensIntramuscular injection of AAV8 in mice and macaques is associated with substantial hepatic targeting and transgene expression.Unique Roles of TLR9- and MyD88-Dependent and -Independent Pathways in Adaptive Immune Responses to AAV-Mediated Gene TransferImmunodominant liver-specific expression suppresses transgene-directed immune responses in murine pompe diseaseSynergistic Efficacy from Gene Therapy with Coreceptor Blockade and a β2-Agonist in Murine Pompe Disease.Enhanced response to enzyme replacement therapy in Pompe disease after the induction of immune tolerance.Evading the immune response upon in vivo gene therapy with viral vectors.Immunity to adeno-associated virus vectors in animals and humans: a continued challenge.Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies.The liver works as a school to educate regulatory immune cells.Improved induction of immune tolerance to factor IX by hepatic AAV-8 gene transfer.Complexity of immune responses to AAV transgene products - Example of factor IX.Impact of the underlying mutation and the route of vector administration on immune responses to factor IX in gene therapy for hemophilia B.Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer.Dynamics of antigen presentation to transgene product-specific CD4+ T cells and of Treg induction upon hepatic AAV gene transfer.Coaxing the liver into preventing autoimmune disease in the brain.Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis.Optimal Immunofluorescent Staining for Human Factor IX and Infiltrating T Cells following Gene Therapy for Hemophilia B.Gene therapy research at the frontiers of viral immunology.Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transferMir-142-3p target sequences reduce transgene-directed immunogenicity following intramuscular adeno-associated virus 1 vector-mediated gene delivery.
P2860
Q27012571-BA8C452D-2DB7-4EC5-AD0E-DF86DA7D85DEQ28264531-1F15D2A1-B2E1-4419-B4BD-314F448665B5Q33490137-C62162A2-CD56-484B-903B-943EEF6C0EF6Q33775537-AEE9535B-1E28-4A51-BE24-4569C005F28DQ33822204-A1874D74-5D18-406B-9617-82E55FB534BCQ34794525-AF3C0FC7-FDA2-4D30-ADA7-DF56E114A065Q34999729-FB6D71A0-D87D-4432-864A-EA205D742184Q35144457-04A9443D-4D34-463C-B499-4EDBCB7AF2A3Q35418068-646FECA4-A71B-4940-91E2-FF3EA7D037F4Q35561776-810D5AA0-8CAF-419E-B451-46EBC598D779Q35988683-B632FA20-4D5D-4E9D-B75A-25F5C9168E66Q36294778-1BDC88B2-6E60-4565-820C-723ACC63A032Q36492202-5D59A318-A1E0-4634-9336-9F1A91E83474Q36644230-7D27B46B-2CCD-428F-BEBA-164567F5F3FDQ37127246-FE7F5292-F388-4160-9F5F-1AA9D2A52AFFQ37342834-3A3E5A75-2227-46D8-A316-902AC9C51912Q37729659-B17B09AD-2E51-4D2B-86AF-8371E8BE4E10Q39302902-74B09DBF-9CF5-4C6B-82CE-FD061AF651EFQ39394803-95CB02C2-F25D-4045-BF3B-F23B3F2F2BE6Q39501844-32A1F315-49B8-432D-BBDD-1782CDCA3D5FQ40049410-D88ECA3D-E5BC-4B85-99C0-975A4AA25040Q40417058-D148D643-9569-4331-8DCB-785F5D5F2AAEQ41844363-C9151762-07C9-4D3C-8318-03BA2BB97E12Q41931070-8FBA2C31-C741-47FE-9D86-BFA3D7E1EC82Q42092752-D8DD92BC-D080-4C6C-9CB3-4BFEA27D5730Q42227245-6FD83392-C967-4115-A991-032E60965EC2Q42786561-BDA6B574-AA45-4922-BCE9-3A5F9E987331Q44861538-7EC7AFE7-09C1-49ED-ADAE-F3231F60629B
P2860
Muscle as a target for supplementary factor IX gene transfer.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Muscle as a target for supplementary factor IX gene transfer.
@en
Muscle as a target for supplementary factor IX gene transfer.
@nl
type
label
Muscle as a target for supplementary factor IX gene transfer.
@en
Muscle as a target for supplementary factor IX gene transfer.
@nl
prefLabel
Muscle as a target for supplementary factor IX gene transfer.
@en
Muscle as a target for supplementary factor IX gene transfer.
@nl
P2093
P356
P1433
P1476
Muscle as a target for supplementary factor IX gene transfer.
@en
P2093
Eric Dobrzynski
Federico Mingozzi
Lauren Hirao
Lixin Wang
Roland W Herzog
P304
P356
10.1089/HUM.2007.042
P577
2007-07-01T00:00:00Z