Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
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Hematopoietic stem cell gene therapy:assessing the relevance of preclinical modelsIntegration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34(+) Cells Correlates With In Vivo Vector Copy Number.Decitabine suspends human CD34+ cell differentiation and proliferation during lentiviral transduction.Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles.High-efficiency transduction of rhesus hematopoietic repopulating cells by a modified HIV1-based lentiviral vector.Evaluation of engraftment and immunological tolerance after reduced intensity conditioning in a rhesus hematopoietic stem cell gene therapy modelKinetics of lentiviral vector transduction in human CD34(+) cellsTransduction of human CD34+ repopulating cells with a self-inactivating lentiviral vector for SCID-X1 produced at clinical scale by a stable cell line.The feasibility of incorporating Vpx into lentiviral gene therapy vectors.TRIM5α variations influence transduction efficiency with lentiviral vectors in both human and rhesus CD34(+) cells in vitro and in vivo.Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency.Current progress on gene therapy for primary immunodeficiencies.RNA Trans-Splicing Targeting Endogenous β-Globin Pre-Messenger RNA in Human Erythroid Cells.Restriction of HIV-1-based lentiviral vectors in adult primary marrow-derived and peripheral mobilized human CD34+ hematopoietic stem and progenitor cells occurs prior to viral DNA integration.Ex vivo expansion of haematopoietic stem/progenitor cells from human umbilical cord blood on acellular scaffolds prepared from MS-5 stromal cell line.Mice engrafted with human hematopoietic stem cells support a human myeloid cell inflammatory response in vivo.Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease.Analysis of ROR1 Protein Expression in Mice with Reconstituted Human Immune System Components.Serum-free Erythroid Differentiation for Efficient Genetic Modification and High-Level Adult Hemoglobin Production.
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P2860
Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
@en
Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
@nl
type
label
Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
@en
Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
@nl
prefLabel
Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
@en
Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
@nl
P2093
P2860
P356
P1433
P1476
Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
@en
P2093
J F Tisdale
J Hayakawa
K N Washington
P2860
P2888
P304
P356
10.1038/GT.2011.63
P577
2011-05-05T00:00:00Z
P5875
P6179
1033147476