In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells.
about
Prodrugs for Gene-Directed Enzyme-Prodrug Therapy (Suicide Gene Therapy)Prodrug converting enzyme gene delivery by L. monocytogenes.Advancement and prospects of tumor gene therapyPurine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancerEnhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene.Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.Cancer gene therapy.Phase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumorsDevelopment of gene therapy in association with clinically used cytotoxic deoxynucleoside analogues.Novel application of lentiviral vectors towards treatment of graft-versus-host disease.PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS.Enzymes to die for: exploiting nucleotide metabolizing enzymes for cancer gene therapy.Pseudomonas aeruginosa NfsB and nitro-CBI-DEI--a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy.Regioselective metalation of 6-methylpurines: synthesis of fluoromethyl purines and related nucleosides for suicide gene therapy of cancer.Expression of the reporter genes lacZ and EGFP in human glioblastoma cells using Listeria monocytogenes as vector for gene transfer.Design and evaluation of 5'-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant.Synergistic antitumor efficacy of suicide/ePNP gene and 6-methylpurine 2'-deoxyriboside via Salmonella against murine tumors.Tumor-targeting Salmonella typhimurium, a natural tool for activation of prodrug 6MePdR and their combination therapy in murine melanoma model.
P2860
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P2860
In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-hans
2000年学术文章
@zh-my
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2000年學術文章
@zh-hant
name
In vivo sensitization of ovari ...... in a small fraction of cells.
@en
In vivo sensitization of ovari ...... in a small fraction of cells.
@nl
type
label
In vivo sensitization of ovari ...... in a small fraction of cells.
@en
In vivo sensitization of ovari ...... in a small fraction of cells.
@nl
prefLabel
In vivo sensitization of ovari ...... in a small fraction of cells.
@en
In vivo sensitization of ovari ...... in a small fraction of cells.
@nl
P2093
P2860
P356
P1433
P1476
In vivo sensitization of ovari ...... in a small fraction of cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.GT.3301286
P577
2000-10-01T00:00:00Z
P5875
P6179
1034379986