about
Mutations in CYP1B1, the gene for cytochrome P4501B1, are the predominant cause of primary congenital glaucoma in Saudi ArabiaSequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1.Genetic, Biochemical and Clinical Insights into Primary Congenital GlaucomaCyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolismGenetic epidemiology of environmental toxicity and cancer susceptibility: human allelic polymorphisms in drug-metabolizing enzyme genes, their functional importance, and nomenclature issues.Drug-metabolizing enzymes, polymorphisms and interindividual response to environmental toxicants.Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptorTranscriptional activation of cytochrome P450 genes by different classes of chemical inducers.Polymorphisms in drug-metabolizing enzymes: what is their clinical relevance and why do they exist?The highly bioactive molecule and signal substance 6-formylindolo[3,2-b]carbazole (FICZ) plays bi-functional roles in cell growth and apoptosis in vitro.
P2860
Q24538744-6456D510-4422-4413-921A-C30DA741F623Q24538817-3A52815A-C243-4860-8572-7ECD9DEC569CQ27022047-0CEFA403-3039-4270-869C-6E23AA5A8D46Q28510829-ECD7EF1C-E42A-4373-ACCB-F210770D4A03Q33639778-27044324-B2BB-4915-877A-CB754CE85BA0Q34093080-C67E20E7-5944-4532-9DEA-68707011DD71Q37021549-350C23F1-7E6D-4B41-A500-AFDCD6C2034CQ41716962-33797055-74FC-4B3B-A63C-2DDAB9B4CDF3Q43109060-AB8B8F71-1B48-477E-87D2-DB89AA531DC9Q48132582-DD990E8A-820D-49C5-99B7-360EBE7BB2D6
P2860
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh-hant
name
Drug metabolism. Growth signal pathways.
@en
Drug metabolism. Growth signal pathways.
@nl
type
label
Drug metabolism. Growth signal pathways.
@en
Drug metabolism. Growth signal pathways.
@nl
prefLabel
Drug metabolism. Growth signal pathways.
@en
Drug metabolism. Growth signal pathways.
@nl
P356
P1433
P1476
Drug metabolism. Growth signal pathways.
@en
P2093
P2888
P304
P356
10.1038/347709A0
P407
P577
1990-10-01T00:00:00Z
P6179
1027027446