Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activation.

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Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors.The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation.

P2860

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Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activation.

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http://www.wikidata.org/entity/Q45938535

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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name

Navigating the conformational ...... during allosteric activation.

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Navigating the conformational ...... during allosteric activation.

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type

Item

label

Navigating the conformational ...... during allosteric activation.

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Navigating the conformational ...... during allosteric activation.

@nl

prefLabel

Navigating the conformational ...... during allosteric activation.

@en

Navigating the conformational ...... during allosteric activation.

@nl

P1476

Navigating the conformational ...... during allosteric activation.

@en

P2093

Emily Labudde

http://www.w3.org/2001/XMLSchema#string

M Claire Cato

http://www.w3.org/2001/XMLSchema#string

Tyler S Beyett

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular basis for activation of G protein-coupled receptor kinases

The Protein Data Bank

MUSCLE: multiple sequence alignment with high accuracy and high throughput

Diversity and modularity of G protein-coupled receptor structures

Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase

Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

Activation of G Protein-Coupled Receptor Kinase 1 Involves Interactions between Its N-Terminal Region and Its Kinase Domain

A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility

VMD: visual molecular dynamics

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16032-16043

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scholarly article

P356

10.1074/JBC.M117.807461

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

292

http://www.w3.org/2001/XMLSchema#string

P50

Barry J Grant

Xin-Qiu Yao

J J Tesmer

P577

2017-08-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28808053

http://www.w3.org/2001/XMLSchema#string

P921

G protein-coupled receptor

P932

5625036

http://www.w3.org/2001/XMLSchema#string

Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activation.

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P2860

P2860

Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activation.

description

name

type

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P1433

P1476

P2093

P2860

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P921

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P356

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P1476

P2093

P2860

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P356

P407

P433

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P50

P577

P698

P921

P932