The 70 carboxyl-terminal amino acids of nascent secretory proteins are protected from proteolysis by the ribosome and the protein translocation apparatus of the endoplasmic reticulum membrane.
about
Membrane topogenesis of a type I signal-anchor protein, mouse synaptotagmin II, on the endoplasmic reticulumStructure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å ResolutionThe organization of engaged and quiescent translocons in the endoplasmic reticulum of mammalian cells.Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.Integration of Shaker-type K+ channel, KAT1, into the endoplasmic reticulum membrane: synergistic insertion of voltage-sensing segments, S3-S4, and independent insertion of pore-forming segments, S5-P-S6Positive charges of translocating polypeptide chain retrieve an upstream marginal hydrophobic segment from the endoplasmic reticulum lumen to the translocon.Nascent peptide-mediated translation elongation arrest coupled with mRNA degradation in the CGS1 gene of ArabidopsisCotranslational partitioning of nascent prion protein into multiple populations at the translocation channel.Molecular mechanism of signal sequence orientation in the endoplasmic reticulum.Ordered membrane insertion of an archaeal opsin in vivo.Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex.Genome-wide analysis of thylakoid-bound ribosomes in maize reveals principles of cotranslational targeting to the thylakoid membraneCotranslational stabilization of Sec62/63 within the ER Sec61 translocon is controlled by distinct substrate-driven translocation events.Versatility of the endoplasmic reticulum protein folding factory.Substrate-specific function of the translocon-associated protein complex during translocation across the ER membraneElectrostatics in the ribosomal tunnel modulate chain elongation rates.Tertiary interactions within the ribosomal exit tunnel.A ribosome-nascent chain sensor of membrane protein biogenesis in Bacillus subtilis.Inhibition of 2A-mediated 'cleavage' of certain artificial polyproteins bearing N-terminal signal sequences.Sucrose control of translation mediated by an upstream open reading frame-encoded peptide.Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide.Folding zones inside the ribosomal exit tunnel.Signal sequence cleavage of peptidyl-tRNA prior to release from the ribosome and translocon.In vitro reconstitution of co-translational D1 insertion reveals a role of the cpSec-Alb3 translocase and Vipp1 in photosystem II biogenesis.
P2860
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P2860
The 70 carboxyl-terminal amino acids of nascent secretory proteins are protected from proteolysis by the ribosome and the protein translocation apparatus of the endoplasmic reticulum membrane.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh-hant
name
The 70 carboxyl-terminal amino ...... ndoplasmic reticulum membrane.
@en
The 70 carboxyl-terminal amino ...... ndoplasmic reticulum membrane.
@nl
type
label
The 70 carboxyl-terminal amino ...... ndoplasmic reticulum membrane.
@en
The 70 carboxyl-terminal amino ...... ndoplasmic reticulum membrane.
@nl
prefLabel
The 70 carboxyl-terminal amino ...... ndoplasmic reticulum membrane.
@en
The 70 carboxyl-terminal amino ...... ndoplasmic reticulum membrane.
@nl
P2860
P356
P1476
The 70 carboxyl-terminal amino ...... ndoplasmic reticulum membrane.
@en
P2093
P2860
P304
P356
10.1074/JBC.270.11.6170
P407
P577
1995-03-01T00:00:00Z