An unfolded protein-induced conformational switch activates mammalian IRE1.
about
Regulation of tumor-stroma interactions by the Unfolded Protein Response.A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response.Ratiometric sensing of BiP-client versus BiP levels by the unfolded protein response determines its signaling amplitude.The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization.Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides.The PERK Arm of the Unfolded Protein Response Negatively Regulates Transmissible Gastroenteritis Virus Replication by Suppressing Protein Translation and Promoting Type I IFN Production.Regulation of Cytokine Production by the Unfolded Protein Response; Implications for Infection and Autoimmunity.IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases.Engineering ER-stress dependent non-conventional mRNA splicing.Ethyl Acetate Extract of cf. Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress
P2860
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P2860
An unfolded protein-induced conformational switch activates mammalian IRE1.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年學術文章
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name
An unfolded protein-induced conformational switch activates mammalian IRE1.
@en
An unfolded protein-induced conformational switch activates mammalian IRE1.
@nl
type
label
An unfolded protein-induced conformational switch activates mammalian IRE1.
@en
An unfolded protein-induced conformational switch activates mammalian IRE1.
@nl
prefLabel
An unfolded protein-induced conformational switch activates mammalian IRE1.
@en
An unfolded protein-induced conformational switch activates mammalian IRE1.
@nl
P2860
P50
P356
P1433
P1476
An unfolded protein-induced conformational switch activates mammalian IRE1
@en
P2093
Crystal P Lee
Feixia Chu
P2860
P356
10.7554/ELIFE.30700
P407
P577
2017-10-03T00:00:00Z