Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development.

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Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders.Stem cell therapy in autism: recent insights Induced pluripotent stem cells as a tool to study brain circuits in autism-related disorders

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Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development.

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2017 nî lūn-bûn

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2017年学术文章

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Stem cell-derived neurons from ...... ties during early development.

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Stem cell-derived neurons from ...... ties during early development.

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Stem cell-derived neurons from ...... ties during early development.

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Stem cell-derived neurons from ...... ties during early development.

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Stem cell-derived neurons from ...... ties during early development.

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Stem cell-derived neurons from ...... ities during early development

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R D Taylor

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R Jagasia

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W Lucchesi

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P2860

Capture of microtubule plus-ends at the actin cortex promotes axophilic neuronal migration by enhancing microtubule tension in the leading process

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

Calcium release-dependent actin flow in the leading process mediates axophilic migration

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

From nose to brain: development of gonadotrophin-releasing hormone-1 neurones

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mp.2017.185

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scholarly article

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10.1038/MP.2017.185

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English

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autism

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Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development.

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P2860

P2860

Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development.

description

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P1433

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