IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
about
The environment of regulatory T cell biology: cytokines, metabolites, and the microbiomeAltered T-cell responses by the periodontal pathogen Porphyromonas gingivalisCD28 co-stimulation down regulates Th17 developmentInterleukin-2 receptor signaling: at the interface between tolerance and immunityAnti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunityMechanisms of T cell organotropismInduced regulatory T cells: mechanisms of conversion and suppressive potentialRegulatory T cells: Mechanisms of suppression and impairment in autoimmune liver diseaseMechanisms underlying the induction of regulatory T cells and its relevance in the adaptive immune response in parasitic infectionsCellular and molecular determinants for the development of natural and induced regulatory T cellsNeoplastic "Black Ops": cancer's subversive tactics in overcoming host defensesLow-dose interleukin-2 therapy: a driver of an imbalance between immune tolerance and autoimmunityVaccination strategies for Parkinson disease: induction of a swift attack or raising tolerance?Review article: chemokines as orchestrators of autoimmune hepatitis and potential therapeutic targetsPorphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer's diseaseTGF-beta: a master of all T cell trades1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitisStrong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signalingAdoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammationCD4(+)CD25(high)CD127(-) regulatory T-cells in COPD: smoke and drugs effectRegulation of multi-organ inflammation in the regulatory T cell-deficient scurfy mice.Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway.Requirement of cognate CD4+ T-cell recognition for the regulation of allospecific CTL by human CD4+ CD127- CD25+ FOXP3+ cells generated in MLR.Dendritic cells decreased the concomitant expanded Tregs and Tregs related IL-35 in cytokine-induced killer cells and increased their cytotoxicity against leukemia cells.Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cellsCytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer.TGF-β activation and function in immunity.Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.Incubation of antigen-sensitized T lymphocytes activated with bryostatin 1 + ionomycin in IL-7 + IL-15 increases yield of cells capable of inducing regression of melanoma metastases compared to culture in IL-2Therapeutic potential of TGF-β-induced CD4(+) Foxp3(+) regulatory T cells in autoimmune diseases.Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ TregMore stories on Th17 cells.The function of BAFF on T helper cells in autoimmunityThe roles of regulatory B cells in cancerDisruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity.Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acidNcf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.Analysis of the transcriptional program of developing induced regulatory T cellsDendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.
P2860
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P2860
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
IL-2 is essential for TGF-beta ...... for expansion of these cells.
@en
IL-2 is essential for TGF-beta ...... for expansion of these cells.
@nl
type
label
IL-2 is essential for TGF-beta ...... for expansion of these cells.
@en
IL-2 is essential for TGF-beta ...... for expansion of these cells.
@nl
prefLabel
IL-2 is essential for TGF-beta ...... for expansion of these cells.
@en
IL-2 is essential for TGF-beta ...... for expansion of these cells.
@nl
P2093
P1476
IL-2 is essential for TGF-beta ...... for expansion of these cells.
@en
P2093
David A Horwitz
J Dixon Gray
Juhua Wang
Song Guo Zheng
P304
P356
10.4049/JIMMUNOL.178.4.2018
P407
P577
2007-02-01T00:00:00Z