Analysis of mutational resistance to trimethoprim in Staphylococcus aureus by genetic and structural modelling techniques.
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Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenesEvolution of MRSA during hospital transmission and intercontinental spreadSingle-molecule sequencing reveals the molecular basis of multidrug-resistance in ST772 methicillin-resistant Staphylococcus aureus.Protein design algorithms predict viable resistance to an experimental antifolateProspective screening of novel antibacterial inhibitors of dihydrofolate reductase for mutational resistanceDeterminants of Genetic Diversity of Spontaneous Drug Resistance in BacteriaEfficacy of iclaprim against wild-type and thymidine kinase-deficient methicillin-resistant Staphylococcus aureus isolates in an in vitro fibrin clot model.Winning the arms race by improving drug discovery against mutating targets.Enzymatic synthesis of poly(catechin)-antibiotic conjugates: an antimicrobial approach for indwelling catheters.In vitro studies indicate a high resistance potential for the lantibiotic nisin in Staphylococcus aureus and define a genetic basis for nisin resistanceRole of mutations in dihydrofolate reductase DfrA (Rv2763c) and thymidylate synthase ThyA (Rv2764c) in Mycobacterium tuberculosis drug resistance.Possible paths and potential barriers to successfully modeling drug resistance.Pathogenic Nocardia cyriacigeorgica and Nocardia nova evolve to resist trimethoprim-sulfamethoxazole by both expected and unexpected pathways.
P2860
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P2860
Analysis of mutational resistance to trimethoprim in Staphylococcus aureus by genetic and structural modelling techniques.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
@wuu
2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Analysis of mutational resista ...... ructural modelling techniques.
@en
Analysis of mutational resista ...... ructural modelling techniques.
@en-gb
Analysis of mutational resista ...... ructural modelling techniques.
@nl
type
label
Analysis of mutational resista ...... ructural modelling techniques.
@en
Analysis of mutational resista ...... ructural modelling techniques.
@en-gb
Analysis of mutational resista ...... ructural modelling techniques.
@nl
prefLabel
Analysis of mutational resista ...... ructural modelling techniques.
@en
Analysis of mutational resista ...... ructural modelling techniques.
@en-gb
Analysis of mutational resista ...... ructural modelling techniques.
@nl
P2093
P2860
P356
P1476
Analysis of mutational resista ...... ructural modelling techniques.
@en
P2093
Anna A Vickers
Ian Chopra
Nicola J Potter
P2860
P304
P356
10.1093/JAC/DKP090
P407
P577
2009-04-21T00:00:00Z