Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6.

Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6.

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http://www.wikidata.org/entity/Q46071774
Inhibitory Mechanism of Caspase-6 Phosphorylation Revealed by Crystal Structures, Molecular Dynamics Simulations, and Biochemical AssaysCaspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice.Novel tetracyclic structures from the synthesis of thiolactone-isatin hybridsPreparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesisTherapeutic approaches to preventing cell death in Huntington diseaseCritical role of the STAT3 pathway in the cardioprotective efficacy of zoniporide in a model of myocardial preservation - the rat isolated working heart.Docking and 3D-QSAR studies on isatin sulfonamide analogues as caspase-3 inhibitors.Molecular mechanisms and potential therapeutical targets in Huntington's disease.Caspase-6 as a novel early target in the treatment of Alzheimer's disease.Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging.Synthesis, Characterization, and Anti-Cancer Activity of Some New N'-(2-Oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazones Derivatives.A label-free LC/MS/MS-based enzymatic activity assay for the detection of genuine caspase inhibitors and SAR development.Elimination of benzene from protonated N-benzylindoline: benzyl cation/proton transfer or direct proton transfer?Exploring a sulfone linker utilizing trimethyl aluminum as a cleavage reagent: solid-phase synthesis of sulfonamides and ureas.Microwave-Assisted Synthesis, Characterization, Antimicrobial and Antioxidant Activity of Some New Isatin DerivativesMicrowave-Assisted Synthesis and Antimicrobial Activity of Some Novel Isatin Schiff Bases Linked to Nicotinic Acid via Certain Amino Acid BridgeMicrowave Synthesis, Characterization, and Antimicrobial Activity of Some Novel Isatin Derivatives
P2860

Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6.

Item
http://www.wikidata.org/entity/Q46071774
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Synthesis and in vitro evaluat ...... ecule inhibitors of caspase-6.
@en
Synthesis and in vitro evaluat ...... ecule inhibitors of caspase-6.
@nl
type
label
Synthesis and in vitro evaluat ...... ecule inhibitors of caspase-6.
@en
Synthesis and in vitro evaluat ...... ecule inhibitors of caspase-6.
@nl
prefLabel
Synthesis and in vitro evaluat ...... ecule inhibitors of caspase-6.
@en
Synthesis and in vitro evaluat ...... ecule inhibitors of caspase-6.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P356
P1433
P1476
Synthesis and in vitro evaluat ...... ecule inhibitors of caspase-6.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698