Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor.
about
IAN family critically regulates survival and development of T lymphocytes.Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEBTOX provides a link between calcineurin activation and CD8 lineage commitmentThemis controls thymocyte selection through regulation of T cell antigen receptor-mediated signalingIP3 receptor-mediated Ca2+ release in naive CD4 T cells dictates their cytokine programReconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancerCell membrane array fabrication and assay technology.Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivityStructural Basis of Cytochrome c Presentation by IE kPositive selection in the thymus: an enigma wrapped in a mystery.Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell functionTransforming growth factor-beta 1 induces antigen-specific unresponsiveness in naive T cellsCalnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexesMyosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formationThe lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cellsDistinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cellsDeficiency of small GTPase Rac2 affects T cell activationCD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.Characterization of a gene encoding two isoforms of a mitochondrial protein up-regulated by cyclosporin A in activated T cellsMacroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central toleranceThe Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineageNck recruitment to the TCR required for ZAP70 activation during thymic development.Dual functions of Nbs1 in the repair of DNA breaks and proliferation ensure proper V(D)J recombination and T-cell development.Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps.Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells.Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC.Hematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cgamma1 Microcluster dynamics during T cell spreadingChallenging the Tritope Model of T cell receptor structure-function relationships with classical data on 'super' and 'allo-MHC' antigens.Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamicsRegulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade.IL-17-producing T cells can augment autoantibody-induced arthritisT cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis.Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.Self-reactive T cells can escape clonal deletion in T-cell receptor V beta 8.1 transgenic mice.TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexesInterferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathwayCD4 T-cell memory can persist in the absence of class II.B cells require "nurturing" by CD4 T cells during development in order to respond in chronic graft-versus-host model of systemic lupus erythematosus.Development and function of T cells in mice with a disrupted CD2 geneFormation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells.
P2860
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P2860
Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh-hant
name
Selective development of CD4+ ...... C-restricted antigen receptor.
@en
Selective development of CD4+ ...... C-restricted antigen receptor.
@nl
type
label
Selective development of CD4+ ...... C-restricted antigen receptor.
@en
Selective development of CD4+ ...... C-restricted antigen receptor.
@nl
prefLabel
Selective development of CD4+ ...... C-restricted antigen receptor.
@en
Selective development of CD4+ ...... C-restricted antigen receptor.
@nl
P2093
P356
P1433
P1476
Selective development of CD4+ ...... C-restricted antigen receptor.
@en
P2093
P2888
P304
P356
10.1038/341746A0
P407
P577
1989-10-01T00:00:00Z
P6179
1026697511