Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps. - Wikidata - awgldk - TriplyDB

Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps.

Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps.

http://www.wikidata.org/entity/Q30482508

about

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1)Molecular regulation of CRAC channels and their role in lymphocyte function Junctophilin-4, a component of the endoplasmic reticulum-plasma membrane junctions, regulates Ca2+ dynamics in T cells 17β-Estradiol inhibits phosphorylation of stromal interaction molecule 1 (STIM1) protein: implication for store-operated calcium entry and chronic lung diseases.STIMulating store-operated Ca(2+) entry.Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals.Molecular basis of calcium signaling in lymphocytes: STIM and ORAI Calcium signaling in immune cells.T-cell receptor complex is essential for Fas signal transduction.Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse.STIM proteins and the endoplasmic reticulum-plasma membrane junctions.A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating.Activation and regulation of store-operated calcium entry.Formation of STIM and Orai complexes: puncta and distal caps.STIM and Orai: the long-awaited constituents of store-operated calcium entry ORAI1 deficiency impairs activated T cell death and enhances T cell survival The third transmembrane segment of orai1 protein modulates Ca2+ release-activated Ca2+ (CRAC) channel gating and permeation properties.Store-operated calcium channels: new perspectives on mechanism and function.Store-operated calcium entry: Mechanisms and modulation.The STIM1-ORAI1 microdomain Imaging techniques for assaying lymphocyte activation in action.Functional stoichiometry of the unitary calcium-release-activated calcium channel STIM1 activation is regulated by a 14 amino acid sequence adjacent to the CRAC activation domain.Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions.Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse.A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activation A Ca2(+ )release-activated Ca2(+) (CRAC) modulatory domain (CMD) within STIM1 mediates fast Ca2(+)-dependent inactivation of ORAI1 channels.Lipid rafts/caveolae as microdomains of calcium signaling.The calcium/NFAT pathway: role in development and function of regulatory T cells.Orai1-NFAT signalling pathway triggered by T cell receptor stimulation.The functional network of ion channels in T lymphocytes B-lymphocyte calcium influx.Functional anatomy of T cell activation and synapse formation.Cholesterol modulates Orai1 channel function Pharmacology of ORAI channels as a tool to understand their physiological functions.Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity.Ca(2+) release-activated Ca(2+) (CRAC) current, structure, and function.

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P2860

Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps.

http://www.wikidata.org/entity/Q30482508

description

2008 nî lūn-bûn

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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

@zh-mo

2008年論文

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2008年论文

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name

Dynamic movement of the calciu ...... cells: puncta and distal caps.

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Dynamic movement of the calciu ...... cells: puncta and distal caps.

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type

label

Dynamic movement of the calciu ...... cells: puncta and distal caps.

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Dynamic movement of the calciu ...... cells: puncta and distal caps.

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prefLabel

Dynamic movement of the calciu ...... cells: puncta and distal caps.

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Dynamic movement of the calciu ...... cells: puncta and distal caps.

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MBC.E08-02-0146

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Molecular Biology of the Cell

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Dynamic movement of the calciu ...... cells: puncta and distal caps.

@en

P2093

Anjana Rao

http://www.w3.org/2001/XMLSchema#string

Carole K Regan

http://www.w3.org/2001/XMLSchema#string

Connie L Sommers

http://www.w3.org/2001/XMLSchema#string

Daniel J Helman

http://www.w3.org/2001/XMLSchema#string

Kelsie M Bernot

http://www.w3.org/2001/XMLSchema#string

Lakshmi Balagopalan

http://www.w3.org/2001/XMLSchema#string

Lawrence E Samelson

http://www.w3.org/2001/XMLSchema#string

Masatsugu Oh-Hora

http://www.w3.org/2001/XMLSchema#string

Sonal Srikanth

http://www.w3.org/2001/XMLSchema#string

Valarie A Barr

http://www.w3.org/2001/XMLSchema#string

P2860

Orai1 and STIM reconstitute store-operated calcium channel function

Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

Orai1 is an essential pore subunit of the CRAC channel

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components

P304

2802-2817

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scholarly article

P356

10.1091/MBC.E08-02-0146

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7

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19

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2008-04-30T00:00:00Z

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18448669

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2441672

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