C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight.

C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight.

Item
http://www.wikidata.org/entity/Q46191269
Mitochondrial fatty acid oxidation in obesityAn Environment-dependent Structural Switch Underlies the Regulation of Carnitine Palmitoyltransferase 1AIncreasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammationUpregulated expression of brain enzymatic markers of arachidonic and docosahexaenoic acid metabolism in a rat model of the metabolic syndromeImportant roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feedingLong-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profileMalonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1aInhibitors of Fatty Acid Synthesis Induce PPAR α -Regulated Fatty Acid β -Oxidative Genes: Synergistic Roles of L-FABP and GlucoseMetabolism and brain cancer.Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs.Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity.Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75.The central administration of C75, a fatty acid synthase inhibitor, activates sympathetic outflow and thermogenesis in interscapular brown adipose tissue.Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake.Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
P2860

C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight.

Item
http://www.wikidata.org/entity/Q46191269
description
2008 nî lūn-bûn
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2008年の論文
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name
C75 is converted to C75-CoA in ...... s food intake and body weight.
@en
C75 is converted to C75-CoA in ...... s food intake and body weight.
@nl
type
label
C75 is converted to C75-CoA in ...... s food intake and body weight.
@en
C75 is converted to C75-CoA in ...... s food intake and body weight.
@nl
prefLabel
C75 is converted to C75-CoA in ...... s food intake and body weight.
@en
C75 is converted to C75-CoA in ...... s food intake and body weight.
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P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
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P5875
P698
P356
P1433
P1476
C75 is converted to C75-CoA in ...... s food intake and body weight.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698