Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.
about
Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesisCABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizuresPrenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disordersThe Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration.A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport, and antioxidant function in Saccharomyces cerevisiae.Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complexGenome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae.Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiaeOverexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.Expression of the human atypical kinase ADCK3 rescues coenzyme Q biosynthesis and phosphorylation of Coq polypeptides in yeast coq8 mutantsMissense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesisMitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain FunctionAarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal AccumulationThioredoxin-family protein EYE2 and Ser/Thr kinase EYE3 play interdependent roles in eyespot assembly.Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis.Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis.Evidence that ubiquinone is a required intermediate for rhodoquinone biosynthesis in Rhodospirillum rubrum.para-Aminobenzoic acid is a precursor in coenzyme Q6 biosynthesis in Saccharomyces cerevisiae.Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis.Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesisCrystallization and preliminary crystallographic studies of UbiG, an O-methyltransferase from Escherichia coliGenetic evidence for an interaction of the UbiG O-methyltransferase with UbiX in Escherichia coli coenzyme Q biosynthesis.Identification of a new gene required for the biosynthesis of rhodoquinone in Rhodospirillum rubrum.Endogenous synthesis of coenzyme Q in eukaryotes.The yeast Coq4 polypeptide organizes a mitochondrial protein complex essential for coenzyme Q biosynthesis.Focal segmental glomerulosclerosis is associated with a PDSS2 haplotype and, independently, with a decreased content of coenzyme Q10.Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants.Molecular genetics of ubiquinone biosynthesis in animals.Regulation of coenzyme Q biosynthesis in yeast: a new complex in the block.Genetic bases and clinical manifestations of coenzyme Q10 (CoQ 10) deficiency.The regulation of coenzyme q biosynthesis in eukaryotic cells: all that yeast can tell us.Genetics of coenzyme q10 deficiency.Balanced CoQ6 biosynthesis is required for lifespan and mitophagy in yeast.Coq10, a mitochondrial coenzyme Q binding protein, is required for proper respiration in Schizosaccharomyces pombe.Comparison of a coq7 deletion mutant with other respiration-defective mutants in fission yeast.The respiratory substrate rhodoquinol induces Q-cycle bypass reactions in the yeast cytochrome bc(1) complex: mechanistic and physiological implications.The Arabidopsis thaliana type I Isopentenyl Diphosphate Isomerases are targeted to multiple subcellular compartments and have overlapping functions in isoprenoid biosynthesis.Biochemistry of Mitochondrial Coenzyme Q Biosynthesis.
P2860
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P2860
Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Coq3 and Coq4 define a polypep ...... he biosynthesis of coenzyme Q.
@en
Coq3 and Coq4 define a polypep ...... he biosynthesis of coenzyme Q.
@nl
type
label
Coq3 and Coq4 define a polypep ...... he biosynthesis of coenzyme Q.
@en
Coq3 and Coq4 define a polypep ...... he biosynthesis of coenzyme Q.
@nl
prefLabel
Coq3 and Coq4 define a polypep ...... he biosynthesis of coenzyme Q.
@en
Coq3 and Coq4 define a polypep ...... he biosynthesis of coenzyme Q.
@nl
P2093
P2860
P356
P1476
Coq3 and Coq4 define a polypep ...... he biosynthesis of coenzyme Q.
@en
P2093
Beth Marbois
Catherine F Clarke
Jeff Strahan
Jennifer N Shepherd
Kym F Faull
Peter T Lee
P2860
P304
20231-20238
P356
10.1074/JBC.M501315200
P407
P50
P577
2005-03-25T00:00:00Z