Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship.

Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship.

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http://www.wikidata.org/entity/Q46265569
Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanismsEvolutionary history and functional characterization of the amphibian xenosensor CAR.Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.Identification and validation of novel human pregnane X receptor activators among prescribed drugs via ligand-based virtual screening.Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoformsIdentification of novel activators of constitutive androstane receptor from FDA-approved drugs by integrated computational and biological approaches.Role of CAR and PXR in xenobiotic sensing and metabolism.Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspectiveComputational modeling of P450s for toxicity prediction.Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor.Constitutive activity and ligand-dependent activation of the nuclear receptor CAR-insights from molecular dynamics simulations.
P2860

Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship.

Item
http://www.wikidata.org/entity/Q46265569
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Insights into ligand-elicited ...... ructure-activity relationship.
@en
Insights into ligand-elicited ...... ructure-activity relationship.
@nl
type
label
Insights into ligand-elicited ...... ructure-activity relationship.
@en
Insights into ligand-elicited ...... ructure-activity relationship.
@nl
prefLabel
Insights into ligand-elicited ...... ructure-activity relationship.
@en
Insights into ligand-elicited ...... ructure-activity relationship.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Insights into ligand-elicited ...... ructure-activity relationship.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698