Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase.

Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase.

Item
http://www.wikidata.org/entity/Q46332821
Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate SynthaseVirtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase.Lipophilic antifolate trimetrexate is a potent inhibitor of Trypanosoma cruzi: prospect for chemotherapy of Chagas' disease.Biochemical and molecular mechanisms of drug resistance in parasites.Promising therapeutic targets for antileishmanial drugs.Antimicrobial dihydrofolate reductase inhibitors--achievements and future options: review.Drug discovery and development for neglected parasitic diseases.Dihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges.Significance and biological importance of pyrimidine in the microbial world.Structural analysis of dihydrofolate reductases enables rationalization of antifolate binding affinities and suggests repurposing possibilities.Pharmacoinformatic Study on the Selective Inhibition of the Protozoan Dihydrofolate Reductase Enzymes.Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes.Development of Chemical Proteomics for the Folateome and Analysis of the Kinetoplastid Folateome
P2860

Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase.

Item
http://www.wikidata.org/entity/Q46332821
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Design, synthesis, and evaluat ...... anial dihydrofolate reductase.
@en
Design, synthesis, and evaluat ...... anial dihydrofolate reductase.
@nl
type
label
Design, synthesis, and evaluat ...... anial dihydrofolate reductase.
@en
Design, synthesis, and evaluat ...... anial dihydrofolate reductase.
@nl
prefLabel
Design, synthesis, and evaluat ...... anial dihydrofolate reductase.
@en
Design, synthesis, and evaluat ...... anial dihydrofolate reductase.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Design, synthesis, and evaluat ...... anial dihydrofolate reductase.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698