Clozapine and the mitogen-activated protein kinase signal transduction pathway: implications for antipsychotic actions.
about
F15063, a potential antipsychotic with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. I. In vitro receptor affinity and efficacy profileEpigenomic profiling reveals DNA-methylation changes associated with major psychosisIdentification of 5-Iodotubercidin as a genotoxic drug with anti-cancer potentialElevated Expression of Serotonin 5-HT(2A) Receptors in the Rat Ventral Tegmental Area Enhances Vulnerability to the Behavioral Effects of CocaineEphA7 regulates spiral ganglion innervation of cochlear hair cells.Distinct neural mechanisms underlying acute and repeated administration of antipsychotic drugs in rat avoidance conditioning.Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotectionEffects of central activation of serotonin 5-HT2A/2C or dopamine D 2/3 receptors on the acute and repeated effects of clozapine in the conditioned avoidance response test.Sex differences in the activity of signalling pathways and expression of G-protein-coupled receptor kinases in the neonatal ventral hippocampal lesion model of schizophrenia.Decreased expression of Sprouty2 in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder: a correlation with BDNF expression.The neurotrophic and neuroprotective effects of psychotropic agents.Psychotropic Medications and Their Effect on Brain Volumes in Childhood Psychopathology.Epigenetic GABAergic targets in schizophrenia and bipolar disorder.Transient domoic acid excitotoxicity increases BDNF expression and activates both MEK- and PKA-dependent neurogenesis in organotypic hippocampal slices.Histone H3 phosphorylation is upregulated in PBMCs of schizophrenia patients in comparison to healthy controls.Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activationInteraction between Neuronal Depolarization and MK-801 in SH-SY5Y Cells and the Rat Cortex.The emerging role of dopamine-glutamate interaction and of the postsynaptic density in bipolar disorder pathophysiology: Implications for treatment.Neuroprogression in schizophrenia: Pathways underpinning clinical staging and therapeutic corollaries.DNA methylation and demethylation as targets for antipsychotic therapy.A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia.Treating the Synapse in Major Psychiatric Disorders: The Role of Postsynaptic Density Network in Dopamine-Glutamate Interplay and Psychopharmacologic Drugs Molecular ActionsClozapine protects PC-12 cells from death due to oxidative stress induced by hydrogen peroxide via a cell-type specific mechanism involving inhibition of extracellular signal-regulated kinase phosphorylation.Effect of dopamine D3 receptor gene polymorphisms and clozapine treatment response: exploratory analysis of nine polymorphisms and meta-analysis of the Ser9Gly variant.The association of DUSP6 gene with schizophrenia and bipolar disorder: its possible role in the development of bipolar disorder.Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia.Role of MKP-1 (DUSP1) in clozapine-induced effects on the ERK1/2 signaling pathway in the rat frontal cortex.In vitro functional characteristics of dopamine D2 receptor partial agonists in second and third messenger-based assays of cloned human dopamine D2Long receptor signalling.
P2860
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P2860
Clozapine and the mitogen-activated protein kinase signal transduction pathway: implications for antipsychotic actions.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Clozapine and the mitogen-acti ...... ons for antipsychotic actions.
@en
Clozapine and the mitogen-acti ...... ons for antipsychotic actions.
@nl
type
label
Clozapine and the mitogen-acti ...... ons for antipsychotic actions.
@en
Clozapine and the mitogen-acti ...... ons for antipsychotic actions.
@nl
prefLabel
Clozapine and the mitogen-acti ...... ons for antipsychotic actions.
@en
Clozapine and the mitogen-acti ...... ons for antipsychotic actions.
@nl
P2093
P1476
Clozapine and the mitogen-acti ...... ons for antipsychotic actions.
@en
P2093
Jeff L Browning
Leigh A Holcomb
Paul B Hicks
Paul C Brandt
Tushar Patel
P304
P356
10.1016/J.BIOPSYCH.2004.12.002
P407
P577
2005-03-01T00:00:00Z