The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation.
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Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells.Understanding the Warburg effect: the metabolic requirements of cell proliferationExpression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpretedBrick by brick: metabolism and tumor cell growthNovel drugs that target the metabolic reprogramming in renal cell cancerMicroRNA in Metabolic Re-Programming and Their Role in TumorigenesisMitochondrial Dysfunction in Cancer and Neurodegenerative Diseases: Spotlight on Fatty Acid Oxidation and Lipoperoxidation ProductsStarved and Asphyxiated: How Can CD8(+) T Cells within a Tumor Microenvironment Prevent Tumor ProgressionAMPK as a potential anticancer target - friend or foe?Molecular biology of gliomas: present and future challengesAutophagy: a targetable linchpin of cancer cell metabolismDrugging the addict: non-oncogene addiction as a target for cancer therapyRegulation and function of proline oxidase under nutrient stressThe eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongationProgress and prospects of reactive oxygen species in metal carcinogenesisSIRT3 and cancer: tumor promoter or suppressor?Differentially expressed proteins in malignant and benign adrenocortical tumorsActivation of β-catenin by oncogenic PIK3CA and EGFR promotes resistance to glucose deprivation by inducing a strong antioxidant responseIsoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cellsThe LKB1-AMPK pathway: metabolism and growth control in tumour suppressionMetabolic reprogramming: a cancer hallmark even warburg did not anticipateThe genomic analysis of lactic acidosis and acidosis response in human cancersOxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect.Metabolic profiling reveals key metabolic features of renal cell carcinoma.Enhancing CD8 T-cell memory by modulating fatty acid metabolismThe glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility.Coordinated metabolic transitions during Drosophila embryogenesis and the onset of aerobic glycolysis.Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition.Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo.Targeting bioenergetics to enhance cancer chemotherapy: mitochondria SLP into apoptosis.Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachmentBone marrow fat: linking adipocyte-induced inflammation with skeletal metastasesFrom genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer.Upregulation of glucose metabolism by NF-κB2/p52 mediates enzalutamide resistance in castration-resistant prostate cancer cells.Metabolism and proliferation share common regulatory pathways in cancer cells.Multiple metabolic alterations exist in mutant PI3K cancers, but only glucose is essential as a nutrient sourceInhibition of fatty acid metabolism reduces human myeloma cells proliferation.MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
P2860
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P2860
The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The glucose dependence of Akt- ...... of fatty acid beta-oxidation.
@en
The glucose dependence of Akt- ...... of fatty acid beta-oxidation.
@nl
type
label
The glucose dependence of Akt- ...... of fatty acid beta-oxidation.
@en
The glucose dependence of Akt- ...... of fatty acid beta-oxidation.
@nl
prefLabel
The glucose dependence of Akt- ...... of fatty acid beta-oxidation.
@en
The glucose dependence of Akt- ...... of fatty acid beta-oxidation.
@nl
P2093
P2860
P921
P356
P1433
P1476
The glucose dependence of Akt- ...... of fatty acid beta-oxidation.
@en
P2093
Craig B Thompson
Daniel E Bauer
Georgia Hatzivassiliou
Monica Buzzai
Ralph J Deberardinis
Rebecca L Elstrom
Russell G Jones
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208622
P407
P577
2005-06-01T00:00:00Z