Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity.
about
Branched polyamines cure prion-infected neuroblastoma cellsPrion hypothesis: the end of the controversy?Darwinian evolution of prions in cell cultureGenerating a prion with bacterially expressed recombinant prion protein.PrionsSpontaneous generation of prion infectivity in fatal familial insomnia knockin miceKuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type miceA short purification process for quantitative isolation of PrPSc from naturally occurring and experimental transmissible spongiform encephalopathies.The mechanism of prion strain propagationAnalysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease.Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles.Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic targetThe strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of diseaseThe physical relationship between infectivity and prion protein aggregates is strain-dependentSynthetic prions with novel strain-specified propertiesEvidence that bank vole PrP is a universal acceptor for prionsMolecular structural basis for polymorphism in Alzheimer's -amyloid fibrilsSolution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoformA brief history of prionsDe novo generation of prion strainsChanging a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers.Strain-specified relative conformational stability of the scrapie prion proteinImmobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form.Prion diseases: dynamics of the infection and properties of the bistable transition.Solid-state NMR as a probe of amyloid structureMolecular, biochemical and genetic characteristics of BSE in CanadaIn situ photodegradation of incorporated polyanion does not alter prion infectivityRelationships between PrPSc stability and incubation time for United States scrapie isolates in a natural host systemDefining the conformational features of anchorless, poorly neuroinvasive prionsSmall ruminant nor98 prions share biochemical features with human gerstmann-sträussler-scheinker disease and variably protease-sensitive prionopathyCritical significance of the region between Helix 1 and 2 for efficient dominant-negative inhibition by conversion-incompetent prion proteinIsolation of a Defective Prion Mutant from Natural ScrapieCorrelation analysis for the incubation period of prion diseaseIsolation of proteinase K-sensitive prions using pronase E and phosphotungstic acidPrion protein: evolution caught en routeAnalysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease PrionsStructural polymorphism of Alzheimer Abeta and other amyloid fibrilsStructural effects of PrP polymorphisms on intra- and interspecies prion transmission.Charge neutralization of the central lysine cluster in prion protein (PrP) promotes PrP(Sc)-like folding of recombinant PrP amyloids.Emergence of a novel bovine spongiform encephalopathy (BSE) prion from an atypical H-type BSE.
P2860
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P2860
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Evidence for the conformation ...... d propagating prion diversity.
@en
Evidence for the conformation ...... d propagating prion diversity.
@nl
type
label
Evidence for the conformation ...... d propagating prion diversity.
@en
Evidence for the conformation ...... d propagating prion diversity.
@nl
prefLabel
Evidence for the conformation ...... d propagating prion diversity.
@en
Evidence for the conformation ...... d propagating prion diversity.
@nl
P2093
P2860
P50
P1433
P1476
Evidence for the conformation ...... d propagating prion diversity.
@en
P2093
Gambetti P
Lugaresi E
Mastrianni J
Montagna P
Telling GC
P2860
P304
P356
10.1126/SCIENCE.274.5295.2079
P407
P577
1996-12-01T00:00:00Z