CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.

CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.

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http://www.wikidata.org/entity/Q46520637

Q46520637

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Role of NADPH oxidase in formation and function of multinucleated giant cells Modulation of CD44 Activity by A6-Peptide Inhibition of the plasma membrane Ca2+ pump by CD44 receptor activation of tyrosine kinases increases the action potential afterhyperpolarization in sensory neurons Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling.AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus.Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance.Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1 Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies.NADPH oxidases regulate CD44 and hyaluronic acid expression in thrombin-treated vascular smooth muscle cells and in atherosclerosis.Low molecular weight hyaluronan-pulsed human dendritic cells showed increased migration capacity and induced resistance to tumor chemoattraction.Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides Updates of reactive oxygen species in melanoma etiology and progression.Reactive oxygen species are indispensable in ovulation Role of versican, hyaluronan and CD44 in ovarian cancer metastasis.ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis.BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration.Chronic UVR causes increased immunostaining of CD44 and accumulation of hyaluronan in mouse epidermis.Hyaluronan fragments promote inflammation by down-regulating the anti-inflammatory A2a receptor.Hyaluronan regulation of endothelial barrier function in cancer.Novel biomarkers and therapeutic targets for optimizing the therapeutic management of melanomas Upregulation of hyaluronan-mediated motility receptor in hepatocellular carcinoma predicts poor survival.An introduction to proteoglycans and their localization Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development Mechanical Characterization of a Dynamic and Tunable Methacrylated Hyaluronic Acid Hydrogel.Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer.miR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2.Comprehensive genomic profiling in diabetic nephropathy reveals the predominance of proinflammatory pathways.Shedding light on proteolytic cleavage of CD44: the responsible sheddase and functional significance of shedding.Hyaluronic acid promotes angiogenesis by inducing RHAMM-TGFβ receptor interaction via CD44-PKCδ.New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity.Antibodies targeting cancer stem cells: a new paradigm in immunotherapy?CD44 in hematological neoplasias.Overexpression of Specific CD44 Isoforms Is Associated with Aggressive Cell Features in Acquired Endocrine Resistance.Bone marrow stromal cells protect acute myeloid leukemia cells from anti-CD44 therapy partly through regulating PI3K/Akt-p27(Kip1) axis.Role of hyaluronan and CD44 in reactive oxygen species-induced mucus hypersecretion.Antitumor activity of hyaluronic acid synthesis inhibitor 4-methylumbelliferone in prostate cancer cells.Platelet-derived growth factor β-receptor, transforming growth factor β type I receptor, and CD44 protein modulate each other's signaling and stability.Sorafenib controls the epithelial‑mesenchymal transition of ovarian cancer cells via EGF and the CD44‑HA signaling pathway in a cell type‑dependent manner.

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P2860

CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.

Item

http://www.wikidata.org/entity/Q46520637

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh-hant

name

CD44-epidermal growth factor r ...... al adhesion kinase, and MMP-2.

@en

CD44-epidermal growth factor r ...... al adhesion kinase, and MMP-2.

@nl

type

Item

label

CD44-epidermal growth factor r ...... al adhesion kinase, and MMP-2.

@en

CD44-epidermal growth factor r ...... al adhesion kinase, and MMP-2.

@nl

prefLabel

CD44-epidermal growth factor r ...... al adhesion kinase, and MMP-2.

@en

CD44-epidermal growth factor r ...... al adhesion kinase, and MMP-2.

@nl

P1476

CD44-epidermal growth factor r ...... al adhesion kinase, and MMP-2.

@en

P2093

Dooil Jeoung

http://www.w3.org/2001/XMLSchema#string

Hansoo Lee

http://www.w3.org/2001/XMLSchema#string

Jongseon Choe

http://www.w3.org/2001/XMLSchema#string

Young-Myeong Kim

http://www.w3.org/2001/XMLSchema#string

Youngmi Kim

http://www.w3.org/2001/XMLSchema#string

Yun-Sil Lee

http://www.w3.org/2001/XMLSchema#string

P2860

Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel

Nox1-dependent reactive oxygen generation is regulated by Rac1

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells

Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells

Epithelial-mesenchymal transitions in tumour progression

Association of focal adhesion kinase with Grb7 and its role in cell migration

Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth

Osteopontin induction of hyaluronan synthase 2 expression promotes breast cancer malignancy

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

P304

22513-22528

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P31

scholarly article

P356

10.1074/JBC.M708319200

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

283

http://www.w3.org/2001/XMLSchema#string

P577

2008-06-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

18577517

http://www.w3.org/2001/XMLSchema#string

CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.

about

P2860

P2860

CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.

description

name

type

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prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698