Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux.
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The ABCs of Candida albicans Multidrug Transporter Cdr1Rational mutational analysis of a multidrug MFS transporter CaMdr1p of Candida albicans by employing a membrane environment based computational approachEmploying information theoretic measures and mutagenesis to identify residues critical for drug-proton antiport function in Mdr1p of Candida albicansThe amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transportFungal PDR transporters: Phylogeny, topology, motifs and function.Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2.FK520 interacts with the discrete intrahelical amino acids of multidrug transporter Cdr1 protein and acts as antagonist to selectively chemosensitize azole-resistant clinical isolates of Candida albicans.Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiaeA New Endogenous Overexpression System of Multidrug Transporters of Candida albicans Suitable for Structural and Functional Studies.Candida drug resistance protein 1, a major multidrug ATP binding cassette transporter of Candida albicans, translocates fluorescent phospholipids in a reconstituted system.Efflux-mediated antifungal drug resistance.Curcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals.Role of Ectopic Gene Conversion in the Evolution of a Candida krusei Pleiotropic Drug Resistance Transporter Family.ABC proteins in yeast and fungal pathogens.Efflux pump proteins in antifungal resistance.Candida Efflux ATPases and Antiporters in Clinical Drug Resistance.Functionally Relevant Residues of Cdr1p: A Multidrug ABC Transporter of Human Pathogenic Candida albicans.Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains.Structure and function analysis of CaMdr1p, a major facilitator superfamily antifungal efflux transporter protein of Candida albicans: identification of amino acid residues critical for drug/H+ transport.Mutations of charged amino acids at the cytoplasmic end of transmembrane helix 2 affect transport activity of the budding yeast multidrug resistance protein Pdr5p.
P2860
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P2860
Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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name
Alanine scanning of transmembr ...... dues critical for drug efflux.
@en
Alanine scanning of transmembr ...... dues critical for drug efflux.
@nl
type
label
Alanine scanning of transmembr ...... dues critical for drug efflux.
@en
Alanine scanning of transmembr ...... dues critical for drug efflux.
@nl
prefLabel
Alanine scanning of transmembr ...... dues critical for drug efflux.
@en
Alanine scanning of transmembr ...... dues critical for drug efflux.
@nl
P2093
P2860
P50
P356
P1476
Alanine scanning of transmembr ...... idues critical for drug efflux
@en
P2093
Luqman Ahmad Khan
Preeti Saini
Rajendra Prasad
Sneha Sudha Komath
Suneet Shukla
Tulika Prasad
P2860
P356
10.1093/JAC/DKI183
P407
P577
2005-06-03T00:00:00Z