Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states. - Wikidata - awgldk - TriplyDB

Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.

Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.

http://www.wikidata.org/entity/Q46567995

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Antigenic variation in Trypanosoma brucei: joining the DOTs Identification of arginine- and lysine-methylation in the proteome of Saccharomyces cerevisiae and its functional implications Developmental roles of the histone lysine demethylases Synthesis of lysine methyltransferase inhibitors Chemical probes of histone lysine methyltransferases Dot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptor Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79 Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases Conformational adaptation drives potent, selective and durable inhibition of the human protein methyltransferase DOT1L Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae.Spt10 and Spt21 are required for transcriptional silencing in Saccharomyces cerevisiae.Histone methylation modifiers in cellular signaling pathways Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle The role of multiple marks in epigenetic silencing and the emergence of a stable bivalent chromatin state Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1 Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di- and tri-methylation on target genes and transformation potential.Quantitative proteomic analysis of histone modifications CREB trans-activation of disruptor of telomeric silencing-1 mediates forskolin inhibition of CTGF transcription in mesangial cells.NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1.Patterns and mechanisms of ancestral histone protein inheritance in budding yeast.A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.Histone H2B C-terminal helix mediates trans-histone H3K4 methylation independent of H2B ubiquitination.Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection Symmetry, asymmetry, and kinetics of silencing establishment in Saccharomyces cerevisiae revealed by single-cell optical assays Analysis of the tolerance to DNA alkylating damage in MEC1 and RAD53 checkpoint mutants of Saccharomyces cerevisiae.Selective inhibitors of protein methyltransferases A dual role of H4K16 acetylation in the establishment of yeast silent chromatin.Breaking an epigenetic chromatin switch: curious features of hysteresis in Saccharomyces cerevisiae telomeric silencing.Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation.Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin H3K79me3T80ph is a Novel Histone Dual Modification and a Mitotic Indicator in Melanoma.A prototypic lysine methyltransferase 4 from archaea with degenerate sequence specificity methylates chromatin proteins Sul7d and Cren7 in different patterns.Controlling histone methylation via trans-histone pathways.Sirtuin 1 functionally and physically interacts with disruptor of telomeric silencing-1 to regulate alpha-ENaC transcription in collecting duct.A lesson learned from the H3.3K27M mutation found in pediatric glioma: a new approach to the study of the function of histone modifications in vivo?Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B.Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome.Sex-specific chromatin landscapes in an ultra-compact chordate genome.Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes.

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P2860

Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.

http://www.wikidata.org/entity/Q46567995

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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Nonprocessive methylation by D ...... tone H3K79 methylation states.

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Nonprocessive methylation by D ...... tone H3K79 methylation states.

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type

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Nonprocessive methylation by D ...... tone H3K79 methylation states.

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Nonprocessive methylation by D ...... tone H3K79 methylation states.

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prefLabel

Nonprocessive methylation by D ...... tone H3K79 methylation states.

@en

Nonprocessive methylation by D ...... tone H3K79 methylation states.

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Nature Structural & Molecular Biology

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Nonprocessive methylation by D ...... tone H3K79 methylation states.

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P2093

Floor Frederiks

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Gideon Oudgenoeg

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Maarten Fornerod

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Manuel Tzouros

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Tibor van Welsem

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P2860

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferases

Structural basis for the product specificity of histone lysine methyltransferases

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

High-resolution profiling of histone methylations in the human genome

The role of chromatin during transcription

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation.

Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase.

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10.1038/NSMB.1432

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6

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15

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Fred van Leeuwen

Jeroen Krijgsveld

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2008-05-30T00:00:00Z

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5338905

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1026808095

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18511943

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