Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain.
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Maintenance of basal levels of autophagy in Huntington's disease mouse models displaying metabolic dysfunctionp62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogrammingAutophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity.p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity.Target acquired: Selective autophagy in cardiometabolic disease.Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.Autophagy-monitoring and autophagy-deficient mice.Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice.Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis.p62 Deficiency Enhances α-Synuclein Pathology in Mice.Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.Muscle dysfunction caused by loss of Magel2 in a mouse model of Prader-Willi and Schaaf-Yang syndromes.Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model.
P2860
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P2860
Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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name
Deficiency of p62/Sequestosome ...... eptin resistance in the brain.
@en
Deficiency of p62/Sequestosome ...... eptin resistance in the brain.
@nl
type
label
Deficiency of p62/Sequestosome ...... eptin resistance in the brain.
@en
Deficiency of p62/Sequestosome ...... eptin resistance in the brain.
@nl
prefLabel
Deficiency of p62/Sequestosome ...... eptin resistance in the brain.
@en
Deficiency of p62/Sequestosome ...... eptin resistance in the brain.
@nl
P2093
P1476
Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain
@en
P2093
Akira Ikeda
Eiji Warabi
Giovanni E Mann
Hiroki Bukawa
Junichi Shoda
Junya Uwayama
Kazuhiro Nakaso
Kosuke Okada
Kyoko Kirii
Noriko Noguchi
P304
14767-14777
P356
10.1523/JNEUROSCI.2954-12.2013
P407
P577
2013-09-01T00:00:00Z