Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.
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Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5Cardiac cAMP: production, hydrolysis, modulation and detectionStructures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitorsStructural basis for the design of selective phosphodiesterase 4B inhibitorsMice deficient in phosphodiesterase-4A display anxiogenic-like behaviorElevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophagesAging-related hyperinflammation in endotoxemia is mediated by the alpha2A-adrenoceptor and CD14/TLR4 pathways.Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice.Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitorAdvances in targeting cyclic nucleotide phosphodiesterasesGram-positive pathogenic bacteria induce a common early response in human monocytesIdentification of plumericin as a potent new inhibitor of the NF-κB pathway with anti-inflammatory activity in vitro and in vivoPhosphodiesterase 4B is essential for T(H)2-cell function and development of airway hyperresponsiveness in allergic asthmaThe effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthmaDistinct roles of adenylyl cyclase VII in regulating the immune responses in micePDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblastsS-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway.Phosphodiesterase-4 (PDE4) molecular pharmacology and Alzheimer's diseaseContribution of mammary epithelial cells to the immune response during early stages of a bacterial infection to Staphylococcus aureus.Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells.Proinflammatory cytokine regulation of cyclic AMP-phosphodiesterase 4 signaling in microglia in vitro and following CNS injury.Cross-talk between PKA-Cβ and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi.The PDE4 inhibitor rolipram prevents NF-kappaB binding activity and proinflammatory cytokine release in human chorionic cellsThe unrecognized effects of phosphodiesterase 4 on epithelial cells in pulmonary inflammation.Identification and Characterization of Baicalin as a Phosphodiesterase 4 Inhibitor.Roflumilast inhibits the release of chemokines and TNF-α from human lung macrophages stimulated with lipopolysaccharide.Postinjury treatment with rolipram increases hemorrhage after traumatic brain injuryImpact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseasesCyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.Therapeutic benefits of phosphodiesterase 4B inhibition after traumatic brain injury.Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling.Roflumilast: a phosphodiesterase-4 inhibitor for the treatment of respiratory disease.Critical role of PDE4D in beta2-adrenoceptor-dependent cAMP signaling in mouse embryonic fibroblastsRolipram attenuates acute oligodendrocyte death in the adult rat ventrolateral funiculus following contusive cervical spinal cord injury.Alcoholic Hepatitis: Steroids vs. PentoxifyllinePhosphodiesterase 4 inhibition in the treatment of psoriasis, psoriatic arthritis and other chronic inflammatory diseases.Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1.Chronic Cognitive Dysfunction after Traumatic Brain Injury Is Improved with a Phosphodiesterase 4B Inhibitor.Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock.
P2860
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P2860
Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.
description
2005 nî lūn-bûn
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2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
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2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
@zh-hant
name
Specific role of phosphodieste ...... ignaling in mouse macrophages.
@en
Specific role of phosphodieste ...... ignaling in mouse macrophages.
@nl
type
label
Specific role of phosphodieste ...... ignaling in mouse macrophages.
@en
Specific role of phosphodieste ...... ignaling in mouse macrophages.
@nl
prefLabel
Specific role of phosphodieste ...... ignaling in mouse macrophages.
@en
Specific role of phosphodieste ...... ignaling in mouse macrophages.
@nl
P2093
P1476
Specific role of phosphodieste ...... ignaling in mouse macrophages.
@en
P2093
Marco Conti
Maria Zoudilova
S-L Catherine Jin
P304
P356
10.4049/JIMMUNOL.175.3.1523
P407
P577
2005-08-01T00:00:00Z