Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver.
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Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasisPPARs and the cardiovascular systemThe Use of SGLT-2 Inhibitors in Type 2 Diabetes and Heart FailureEffects of PPARalpha on cardiac glucose metabolism: a transcriptional equivalent of the glucose-fatty acid cycle?Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cellsCrif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in miceCardiac-specific ablation of ARNT leads to lipotoxicity and cardiomyopathy.New insights into insulin resistance in the diabetic heart.Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease.DGAT1 deficiency decreases PPAR expression and does not lead to lipotoxicity in cardiac and skeletal muscle.Mitochondria and Oxidative Stress in the Cardiorenal Metabolic Syndrome.Fenofibrate inhibited the differentiation of T helper 17 cells in vitro.Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion.Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failureProtective Effect of Peroxisome Proliferator-Activated Receptor α Activation against Cardiac Ischemia-Reperfusion Injury Is Related to Upregulation of Uncoupling Protein-3The PPARalpha-PGC-1alpha Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium.Should We Use PPAR Agonists to Reduce Cardiovascular Risk?Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes.Perturbations in the gene regulatory pathways controlling mitochondrial energy production in the failing heart.Insulin resistance: metabolic mechanisms and consequences in the heart.Myocardial AKT: the omnipresent nexus.Testosterone Replacement Modulates Cardiac Metabolic Remodeling after Myocardial Infarction by Upregulating PPARα.Type 2 diabetes, mitochondrial biology and the heart.Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.Lipoprotein lipase activity is required for cardiac lipid droplet production.PPARs: diverse regulators in energy metabolism and metabolic diseases.Peroxisome proliferator activated receptor-alpha (PPARα) and PPAR gamma coactivator-1alpha (PGC-1α) regulation of cardiac metabolism in diabetes.Lipotoxicity and cardiac dysfunction in mammals and Drosophila.Sphingolipids, lipotoxic cardiomyopathy, and cardiac failure.Gliptin therapy reduces hepatic and myocardial fat in type 2 diabetic patients Gliptins and cardiometabolic risk.Rosiglitazone-loaded nanospheres for modulating macrophage-specific inflammation in obesity.A novel high-throughput screening assay for putative antidiabetic agents through PPARalpha interactions.Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha.Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity.Too much or not enough of a good thing? Cardiac glucolipotoxicity versus lipoprotection.Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart.Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart.Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling.Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth.Changes in myocardial mechanics in patients with obesity following major weight loss after bariatric surgery.
P2860
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P2860
Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Cardiac-specific overexpressio ...... resistance in heart and liver.
@en
Cardiac-specific overexpressio ...... resistance in heart and liver.
@nl
type
label
Cardiac-specific overexpressio ...... resistance in heart and liver.
@en
Cardiac-specific overexpressio ...... resistance in heart and liver.
@nl
prefLabel
Cardiac-specific overexpressio ...... resistance in heart and liver.
@en
Cardiac-specific overexpressio ...... resistance in heart and liver.
@nl
P2093
P1433
P1476
Cardiac-specific overexpressio ...... resistance in heart and liver.
@en
P2093
Anton M Bennett
April Kalinowski
Beverly Rothermel
Brian N Finck
Cheryl Danton
Daniel P Kelly
Eun-Gyoung Hong
Gary W Cline
Hyo-Jeong Kim
Jason K Kim
P304
P356
10.2337/DIABETES.54.9.2514
P407
P577
2005-09-01T00:00:00Z