Uncoupling protein 1 expression in murine skeletal muscle increases AMPK activation, glucose turnover, and insulin sensitivity in vivo.
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UCP4 overexpression improves fatty acid oxidation and insulin sensitivity in L6 myocytesThe role of mitochondria in the pathophysiology of skeletal muscle insulin resistance.Gender dimorphism in skeletal muscle proteome between lean and diet-induced obese rats.Absence of RIP140 reveals a pathway regulating glut4-dependent glucose uptake in oxidative skeletal muscle through UCP1-mediated activation of AMPK.Calorie restriction in mice overexpressing UCP3: evidence that prior mitochondrial uncoupling alters response.Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice.Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance.Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways.Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice.Activation of AMPKα2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrityActivation of muscular TrkB by its small molecular agonist 7,8-dihydroxyflavone sex-dependently regulates energy metabolism in diet-induced obese mice.The genetic pleiotropy of musculoskeletal aging.Skeletal muscle mitochondrial uncoupling prevents diabetes but not obesity in NZO mice, a model for polygenic diabesity.Deregulated coenzyme A, loss of metabolic flexibility and diabetes.Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat diet-induced obesity.Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity.FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process.Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine.Augmenting energy expenditure by mitochondrial uncoupling: a role of AMP-activated protein kinase.Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action.Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system.Loss of UCP1 exacerbates Western diet-induced glycemic dysregulation independent of changes in body weight in female mice.A pivotal role of AMPK signaling in medicarpin-mediated formation of brown and beige adipocytes from C3H10T1/2 mesenchymal stem cells.Brown adipocyte progenitor population is modified in obese and diabetic skeletal muscle.
P2860
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P2860
Uncoupling protein 1 expression in murine skeletal muscle increases AMPK activation, glucose turnover, and insulin sensitivity in vivo.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
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2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
@zh-hant
name
Uncoupling protein 1 expressio ...... d insulin sensitivity in vivo.
@en
Uncoupling protein 1 expressio ...... d insulin sensitivity in vivo.
@nl
type
label
Uncoupling protein 1 expressio ...... d insulin sensitivity in vivo.
@en
Uncoupling protein 1 expressio ...... d insulin sensitivity in vivo.
@nl
prefLabel
Uncoupling protein 1 expressio ...... d insulin sensitivity in vivo.
@en
Uncoupling protein 1 expressio ...... d insulin sensitivity in vivo.
@nl
P2093
P2860
P50
P1476
Uncoupling protein 1 expressio ...... d insulin sensitivity in vivo.
@en
P2093
Annette Schürmann
Farshad Mirhashemi
Julia Richter
Robert Augustin
Susanne Neschen
Yvonne Katterle
P2860
P304
P356
10.1152/PHYSIOLGENOMICS.00226.2007
P577
2008-03-18T00:00:00Z