Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34.
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The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionCross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysisThe mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral responseStructure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrateMechanism of ubiquitin-chain formation by the human anaphase-promoting complexAllosteric regulation of E2:E3 interactions promote a processive ubiquitination machineRapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substratesTRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexesIdentification, analysis, and prediction of protein ubiquitination sitesQuantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradationProtein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processesBuilding and remodelling Cullin-RING E3 ubiquitin ligasesAllosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2pMechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g260th residues of ubiquitin and Nedd8 are located out of E2-binding surfaces, but are important for K48 ubiquitin-linkageSolution structure and dynamics of human ubiquitin conjugating enzyme Ube2g2A Dual E3 Mechanism for Rub1 Ligation to Cdc53Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongationE3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimerA Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function ScreenStructural basis for ligase-specific conjugation of linear ubiquitin chains by HOIPStructural insight into plant programmed cell death mediated by BAG proteins in Arabidopsis thalianaThe essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4.Synthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5.Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo.Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3E2s: structurally economical and functionally repleteAn acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymesDimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chainsEssential role for ubiquitin-ubiquitin-conjugating enzyme interaction in ubiquitin discharge from Cdc34 to substrateDegradation of the Saccharomyces cerevisiae mating-type regulator alpha1: genetic dissection of cis-determinants and trans-acting pathwaysSAG/RBX2 E3 ligase complexes with UBCH10 and UBE2S E2s to ubiquitylate β-TrCP1 via K11-linkage for degradationBuilding ubiquitin chains: E2 enzymes at workReal-time detection of N-end rule-mediated ubiquitination via fluorescently labeled substrate probes.BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300.Paths of long-range communication in the E2 enzymes of family 3: a molecular dynamics investigation.
P2860
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P2860
Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Mechanism of lysine 48-linked ...... itin-ligase complex SCF-Cdc34.
@en
Mechanism of lysine 48-linked ...... itin-ligase complex SCF-Cdc34.
@nl
type
label
Mechanism of lysine 48-linked ...... itin-ligase complex SCF-Cdc34.
@en
Mechanism of lysine 48-linked ...... itin-ligase complex SCF-Cdc34.
@nl
prefLabel
Mechanism of lysine 48-linked ...... itin-ligase complex SCF-Cdc34.
@en
Mechanism of lysine 48-linked ...... itin-ligase complex SCF-Cdc34.
@nl
P1433
P1476
Mechanism of lysine 48-linked ...... itin-ligase complex SCF-Cdc34.
@en
P2093
Matthew D Petroski
Raymond J Deshaies
P304
P356
10.1016/J.CELL.2005.09.033
P407
P577
2005-12-01T00:00:00Z