Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool. - Wikidata - awgldk - TriplyDB

Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool.

Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool.

http://www.wikidata.org/entity/Q46716460

about

Mammary stem cells and the differentiation hierarchy: current status and perspectives Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium Membrane-localized estrogen receptor α is required for normal organ development and function.Chromatin Memory in the Development of Human Cancers Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells.Loss of EZH2 results in precocious mammary gland development and activation of STAT5-dependent genes.EZH2 inhibition promotes epithelial-to-mesenchymal transition in ovarian cancer cells.Axes of differentiation in breast cancer: untangling stemness, lineage identity, and the epithelial to mesenchymal transition.The roles of ncRNAs and histone-modifiers in regulating breast cancer stem cells.Pubertal Mammary Gland Development: Elucidation of In Vivo Morphogenesis Using Murine Models.Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?Cell lineage determinants as regulators of breast cancer metastasis.Prolactin Alters the Mammary Epithelial Hierarchy, Increasing Progenitors and Facilitating Ovarian Steroid Action Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program.LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages Epigenomics of mammary gland development Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities

P2860

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P2860

Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool.

http://www.wikidata.org/entity/Q46716460

description

2013 nî lūn-bûn

@nan

2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh-hant

name

Polycomb group gene Ezh2 regul ...... s the luminal progenitor pool.

@en

Polycomb group gene Ezh2 regul ...... s the luminal progenitor pool.

@nl

type

label

Polycomb group gene Ezh2 regul ...... s the luminal progenitor pool.

@en

Polycomb group gene Ezh2 regul ...... s the luminal progenitor pool.

@nl

prefLabel

Polycomb group gene Ezh2 regul ...... s the luminal progenitor pool.

@en

Polycomb group gene Ezh2 regul ...... s the luminal progenitor pool.

@nl

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Polycomb group gene Ezh2 regul ...... ns the luminal progenitor pool

@en

P2093

Alexandra Pietersen

http://www.w3.org/2001/XMLSchema#string

Ellen Tanger

http://www.w3.org/2001/XMLSchema#string

Ellen Wientjens

http://www.w3.org/2001/XMLSchema#string

Inka Pawlitzky

http://www.w3.org/2001/XMLSchema#string

Jos Jonkers

http://www.w3.org/2001/XMLSchema#string

Jost Seibler

http://www.w3.org/2001/XMLSchema#string

Karim Nacerddine

http://www.w3.org/2001/XMLSchema#string

Maarten van Lohuizen

http://www.w3.org/2001/XMLSchema#string

Paulien Cornelissen-Steijger

http://www.w3.org/2001/XMLSchema#string

Vincent Beuger

http://www.w3.org/2001/XMLSchema#string

P2860

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland

Lactation defect in a widely used MMTV-Cre transgenic line of mice

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation

Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis

Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium

Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells

Expression profiling reveals off-target gene regulation by RNAi

Generation of a functional mammary gland from a single stem cell

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1910-1920

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scholarly article

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10.1002/STEM.1437

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9

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31

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23712803

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