Insulin rapidly increases diacylglycerol by activating de novo phosphatidic acid synthesis.
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Interleukin-1 generates transmembrane signals from phospholipids through novel pathways in cultured rat mesangial cellsInsulin and phorbol ester stimulate conductive Na+ transport through a common pathway.Sphingosine, an inhibitor of protein kinase C, suppresses the insulin-like effects of growth hormone in rat adipocytes.Long-term effect of insulin on glucose transport and insulin binding in cultured adipocytes from normal and obese humans with and without non-insulin-dependent diabetes.Hepatic Atypical Protein Kinase C: An Inherited Survival-Longevity Gene that Now Fuels Insulin-Resistant Syndromes of Obesity, the Metabolic Syndrome and Type 2 Diabetes MellitusDeregulation of hamster fibroblast proliferation by mutated ras oncogenes is not mediated by constitutive activation of phosphoinositide-specific phospholipase C.Quantification of diacylglycerol molecular species in biological samples by electrospray ionization mass spectrometry after one-step derivatizationInsulin, oxytocin, and vasopressin stimulate protein kinase C activity in adipocyte plasma membranes.Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the Glut1 glucose transporter.The mitogenic activities of phosphatidate are acyl-chain-length dependent and calcium independent in C3H/10T1/2 cells.Possible involvement of normal p21 H-ras in the insulin/insulinlike growth factor 1 signal transduction pathway.Mitogenic signal transduction in normal and transformed 32D hematopoietic cells.Identification of two cytosolic diacylglycerol kinase isoforms in rat brain, and in NIH-3T3 and ras-transformed fibroblastsSustained increase in 1,2-diacylglycerol precedes DNA synthesis in epidermal-growth-factor-stimulated fibroblasts. Evidence for stimulated phosphatidylcholine hydrolysis.Mechanisms whereby insulin increases diacylglycerol in BC3H-1 myocytes.Long-term treatment of isolated rat soleus muscle with phorbol ester leads to loss of contraction-induced glucose transportEnzymatic and transcriptional regulation of the cytoplasmic acetyl-CoA hydrolase ACOT12Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-alpha in normal human skin fibroblasts and keratinocytesPlatelet-derived growth factor stimulates synthesis of 1,2-diacylglycerol from monoacylglycerol in Balb/c 3T3 cells.Signal transduction in EJ-H-ras-transformed cells: de novo synthesis of diacylglycerol and subversion of agonist-stimulated inositol lipid metabolism.Diacylglycerol directly stimulates the insulin receptor tyrosine kinase.Insulin provokes co-ordinated increases in the synthesis of phosphatidylinositol, phosphatidylinositol phosphates and the phosphatidylinositol-glycan in BC3H-1 myocytes.Phospholipase D activation by the mitogens platelet-derived growth factor and 12-O-tetradecanoylphorbol 13-acetate in NIH-3T3 cells.Insulin-like effects of epidermal growth factor and insulin-like growth factor-I on [3H]2-deoxyglucose uptake, diacylglycerol generation and protein kinase C activation in BC3H-1 myocytes.Correction of abnormal small intestinal cytosolic protein kinase C activity in streptozotocin-induced diabetes by insulin therapy.Free fatty acids induce cell differentiation to infective forms in Trypanosoma cruzi.1,2-Diacylglycerol and ceramide levels in rat liver and skeletal muscle in vivo.Interactions of TPA and insulin on Na+ transport across frog skin.Induction of phosphatidic acid by fibroblast growth factor in cultured baby hamster kidney fibroblasts.
P2860
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P2860
Insulin rapidly increases diacylglycerol by activating de novo phosphatidic acid synthesis.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh-hant
name
Insulin rapidly increases diac ...... o phosphatidic acid synthesis.
@en
Insulin rapidly increases diac ...... o phosphatidic acid synthesis.
@nl
type
label
Insulin rapidly increases diac ...... o phosphatidic acid synthesis.
@en
Insulin rapidly increases diac ...... o phosphatidic acid synthesis.
@nl
prefLabel
Insulin rapidly increases diac ...... o phosphatidic acid synthesis.
@en
Insulin rapidly increases diac ...... o phosphatidic acid synthesis.
@nl
P2093
P356
P1433
P1476
Insulin rapidly increases diac ...... o phosphatidic acid synthesis.
@en
P2093
P304
P356
10.1126/SCIENCE.3107122
P407
P577
1987-05-01T00:00:00Z