Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms.
about
Toxicity of amphetamines: an updateMechanisms of dopamine transporter regulation in normal and disease statesA receptor mechanism for methamphetamine action in dopamine transporter regulation in brainTrace amine-associated receptor 1 as a monoaminergic modulator in brainBehavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporterRole of the dopamine transporter in the action of psychostimulants, nicotine, and other drugs of abuseAltered dopamine transporter function and phosphorylation following chronic cocaine self-administration and extinction in ratsThe rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants.Dopamine transporter trafficking: rapid response on demand.PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.Methamphetamine abuse, HIV infection, and neurotoxicity.Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder.Rapid substrate-induced down-regulation in function and surface localization of dopamine transporters: rat dorsal striatum versus nucleus accumbens.Syntaxin 1A regulates dopamine transporter activity, phosphorylation and surface expression.Involvement of threonine 258 and serine 259 motif in amphetamine-induced norepinephrine transporter endocytosis.Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters.Striatal dopamine neurotransmission: regulation of release and uptakeRegulation of monoamine transporters: Role of transporter phosphorylation.SLC6 transporters: structure, function, regulation, disease association and therapeuticsRegulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease.Amphetamine and methamphetamine differentially affect dopamine transporters in vitro and in vivo.Cocaine up-regulation of the norepinephrine transporter requires threonine 30 phosphorylation by p38 mitogen-activated protein kinaseThree ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporterMechanisms of methamphetamine-induced dopaminergic neurotoxicity.Cocaine facilitates PKC maturation by upregulating its phosphorylation at the activation loop in rat striatal neurons in vivo.Amphetamines, new psychoactive drugs and the monoamine transporter cycle.Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux.Reciprocal Phosphorylation and Palmitoylation Control Dopamine Transporter Kinetics.Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding.The role of the plasmalemmal dopamine and vesicular monoamine transporters in methamphetamine-induced dopaminergic deficits.Neurotoxic profiles of HIV, psychostimulant drugs of abuse, and their concerted effect on the brain: current status of dopamine system vulnerability in NeuroAIDSHIV-1 Tat protein decreases dopamine transporter cell surface expression and vesicular monoamine transporter-2 function in rat striatal synaptosomesProline-directed phosphorylation of the dopamine transporter N-terminal domain.Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transportersN-terminus regulation of VMAT2 mediates methamphetamine-stimulated efflux.Methamphetamine self-administration acutely decreases monoaminergic transporter function.Potentiated striatal dopamine release leads to hyperdopaminergia in female brain-derived neurotrophic factor heterozygous mice.Dopamine release mediated by the dopamine transporter, facts and consequences.Phospho-specific antibodies targeting the amino terminus of the human dopamine transporter.
P2860
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P2860
Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Psychoactive substrates stimul ...... kinase C-dependent mechanisms.
@en
Psychoactive substrates stimul ...... kinase C-dependent mechanisms.
@nl
type
label
Psychoactive substrates stimul ...... kinase C-dependent mechanisms.
@en
Psychoactive substrates stimul ...... kinase C-dependent mechanisms.
@nl
prefLabel
Psychoactive substrates stimul ...... kinase C-dependent mechanisms.
@en
Psychoactive substrates stimul ...... kinase C-dependent mechanisms.
@nl
P2860
P356
P1476
Psychoactive substrates stimul ...... kinase C-dependent mechanisms
@en
P2093
James D Foster
Roxanne A Vaughan
P2860
P304
40442-40449
P356
10.1074/JBC.M501969200
P407
P577
2005-10-04T00:00:00Z