Endothelial nitric oxide synthase activation by tumor necrosis factor alpha through neutral sphingomyelinase 2, sphingosine kinase 1, and sphingosine 1 phosphate receptors: a novel pathway relevant to the pathophysiology of endothelium.
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Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join ForcesExercise Modulates Oxidative Stress and Inflammation in Aging and Cardiovascular DiseasesSphingosine-1-phosphate in chronic intestinal inflammation and cancerRoles and regulation of neutral sphingomyelinase-2 in cellular and pathological processesSphingosine-1-phosphate as a mediator of high-density lipoprotein effects in cardiovascular protectionNeutral sphingomyelinase 2 is palmitoylated on multiple cysteine residues. Role of palmitoylation in subcellular localizationRegulation of obesity and insulin resistance by nitric oxideStress-induced sphingolipid signaling: role of type-2 neutral sphingomyelinase in murine cell apoptosis and proliferation.Role of sphingosine kinase/S1P axis in ECM remodeling of cardiac cells elicited by relaxinSphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids.Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation.Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide.Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching.Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2.Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system.Many ceramides.Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1betaSphingolipid metabolism, oxidant signaling, and contractile function of skeletal muscleGPR40/FFA1 and neutral sphingomyelinase are involved in palmitate-boosted inflammatory response of microvascular endothelial cells to LPS.The outs and the ins of sphingosine-1-phosphate in immunityTargeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brainThe role of nitric oxide in mediating tumour blood flow.Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide productionThe apolipoprotein m-sphingosine-1-phosphate axis: biological relevance in lipoprotein metabolism, lipid disorders and atherosclerosisHuman squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cellsNeutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells.Role of TNF-alpha in vascular dysfunction.A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis.Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1.The role of inflammatory cytokines in endothelial dysfunctionNitric oxide and sphingolipids: mechanisms of interaction and role in cellular pathophysiology.Inflammatory cytokines in vascular dysfunction and vascular disease.FOXO3a regulates oxygen-responsive expression of tumor necrosis factor receptor 2 in human dermal microvascular endothelial cells.The role of sphingolipid signalling in diabetes‑associated pathologies (Review).Vascular function and inflammation in rheumatoid arthritis: the role of physical activity.Biological roles of Acid and neutral sphingomyelinases and their regulation by nitric oxide.Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.Role of Reactive Oxygen Species in Tumor Necrosis Factor-alpha Induced Endothelial Dysfunction.Sphingosine 1-phosphate in coagulation and inflammation.
P2860
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P2860
Endothelial nitric oxide synthase activation by tumor necrosis factor alpha through neutral sphingomyelinase 2, sphingosine kinase 1, and sphingosine 1 phosphate receptors: a novel pathway relevant to the pathophysiology of endothelium.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Endothelial nitric oxide synth ...... athophysiology of endothelium.
@en
Endothelial nitric oxide synth ...... athophysiology of endothelium.
@nl
type
label
Endothelial nitric oxide synth ...... athophysiology of endothelium.
@en
Endothelial nitric oxide synth ...... athophysiology of endothelium.
@nl
prefLabel
Endothelial nitric oxide synth ...... athophysiology of endothelium.
@en
Endothelial nitric oxide synth ...... athophysiology of endothelium.
@nl
P50
P1476
Endothelial nitric oxide synth ...... athophysiology of endothelium.
@en
P2093
Elisabetta Meacci
P304
P356
10.1161/01.ATV.0000194074.59584.42
P407
P577
2005-11-03T00:00:00Z