Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.
about
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapseEzrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.T cell activationCD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76Dynamic Regulation of TCR-Microclusters and the Microsynapse for T Cell ActivationMolecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling UnitsConcerning immune synapses: a spatiotemporal timelineUltrasensitivity in the Cofilin Signaling Module: A Mechanism for Tuning T Cell ResponsesFunction and Dynamics of Tetraspanins during Antigen Recognition and Immunological Synapse FormationDisturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus ErythematosusT Lymphocyte-Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific ImmunityHuman Immunodeficiencies Related to Defective APC/T Cell InteractionExperimental and theoretical bases for mechanisms of antigen discrimination by T cellsRegulation of T-cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasmCell biological steps and checkpoints in accessing NK cell cytotoxicityThe immunological synapse: the gateway to the HIV reservoirImpaired T-Cell Function in B-Cell Lymphoma: A Direct Consequence of Events at the Immunological Synapse?Signaling at neuro/immune synapsesSuper-resolution characterization of TCR-dependent signaling clustersControversy and consensus regarding myosin II function at the immunological synapseT cell antigen recognition at the cell membraneMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseEarly Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin NetworkLigand mobility modulates immunological synapse formation and T cell activationIntegrins Influence the Size and Dynamics of Signaling Microclusters in a Pyk2-dependent MannerInitiation of T cell signaling by CD45 segregation at 'close contacts'TIRF imaging of Fc gamma receptor microclusters dynamics and signaling on macrophages during frustrated phagocytosisElastohydrodynamics and Kinetics of Protein Patterning in the Immunological SynapseRemodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopyAltered actin centripetal retrograde flow in physically restricted immunological synapsesA conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signalingT Cell Receptors are Structures Capable of Initiating Signaling in the Absence of Large Conformational RearrangementsCD28 and CTLA-4 coreceptor expression and signal transductionCish actively silences TCR signaling in CD8+ T cells to maintain tumor toleranceComputational investigations into the origins of short-term biochemical memory in T cell activationThe lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cellsRhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte developmentPOLKADOTS are foci of functional interactions in T-Cell receptor-mediated signaling to NF-kappaB.Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discriminationT cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster.
P2860
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P2860
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Newly generated T cell recepto ...... cruitment of Zap70 and SLP-76.
@en
Newly generated T cell recepto ...... cruitment of Zap70 and SLP-76.
@nl
type
label
Newly generated T cell recepto ...... cruitment of Zap70 and SLP-76.
@en
Newly generated T cell recepto ...... cruitment of Zap70 and SLP-76.
@nl
prefLabel
Newly generated T cell recepto ...... cruitment of Zap70 and SLP-76.
@en
Newly generated T cell recepto ...... cruitment of Zap70 and SLP-76.
@nl
P2093
P50
P356
P1433
P1476
Newly generated T cell recepto ...... cruitment of Zap70 and SLP-76.
@en
P2093
Kumiko Sakata-Sogawa
Michio Hiroshima
Tadashi Yokosuka
Wakana Kobayashi
P2888
P304
P356
10.1038/NI1272
P407
P577
2005-11-06T00:00:00Z
P5875
P6179
1048674669